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A Clinical Atlas of 101 Common Skin Diseases

Acanthosis Nigricans

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Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds.

A Clinical Atlas of 101 Common Skin Diseases

Acanthosis Nigricans

Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds. This disease has a predilection for intertriginous regions. The condition may develop consequent to…

Therapeutic Strategies in Dermatology

Oral Hairy Leukoplakia: Key Points

Key Points OHL is caused by infection with Epstein-Barr virus (EBV), and usually presents as corrugated white plaques of the lateral tongue. OHL is a clinical manifestation of immunosuppression and classically presents in the setting of HIV infecti…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Benign, Pseudo, or Malignant Acanthosis Nigricans?

…disappears when he loses it.” Curth HO. Significance of acanthosis nigricans. Arch Dermatol 1952;66:80-100. “Twenty-four children suspected as benign acanthosis nigricans underwent skin biopsy and its association with nonalcoholic stea…

Differential Diagnosis in Dermatopathology

Nevus verrucosus vs. Acanthosis nigricans

Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds. This disease has a predilection for intertriginous regions. The condition may develop consequent to…

A Clinical Atlas of 101 Common Skin Diseases

Seborrheic Dermatitis

An inflammatory process that consists of tiny papules covered by prominent scales and localized typically to the “seborrheic region,” namely, scalp, forehead, eyebrows, malar eminences, paranasal and nasolabial folds, and retroauricular…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 11.11.1A: Perivascular dermatosis, lichenoid + 11.11.1B: Lymphocytes, many necrotic keratocytes and a subepidermal cleft = Lichen planus-like keratosis, early  Because lichen planus-like keratosis often is misinterpreted clinically…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.23.1A: Perivascular dermatitis, psoriasiform + 10.23.1B: Orthokeratosis, hypergranulosis, acanthosis, proliferation of infundibular and eccrine ductal keratocytes, and coarse bundles of collagen in vertical streaks = Lichen simp…

Differential Diagnosis in Dermatopathology

Discussions

…ally keratoses. The velvety, tan to gray-brown excrescences of acanthosis nigricans tend to develop especially in intertriginous regions, such as the axillae and groin; the neck, umbilicus, and nipples are other sites favored. Conventionally, acantho…

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