Dermatology Practical & Conceptual

Papillary adenocarcinoma in situ of the skin: report of four cases

Abstract Although rare isolated cases of adenocarcinoma in situ of skin have been reported in the literature, adenocarcinoma in situ of skin as a concept and as a diagnostic category has not been established in the field of dermatopathology. In this…

A Clinical Atlas of 101 Common Skin Diseases

Acanthosis Nigricans

Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds. This disease has a predilection for intertriginous regions. The condition may develop consequent to…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mammary and Extramammary Paget’s Disease?

“Extramammary Paget’s disease is a carcinoma of the ducts of apocrine sweat glands, with the invasion of carcinoma cells (Paget’s cells) into the epidermis and into the glandular portion of the sweat gland.” Braun-Falco O,…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Benign, Pseudo, or Malignant Acanthosis Nigricans?

…igricans and tripe palms secondary to an underlying pancreatic adenocarcinoma.” McGinness J, Greer K. Malignant acanthosis nigricans and tripe palms associated with pancreatic adenocarcinoma. Cutis 2006 78(1):37-40. Acanthosis nigricans affect…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Origin of Adnexal Neoplasms?

“Thus one needs to bear in mind the information required of a pathologist about a particular tumour, which can be summarized as follows: 1. What is the origin of the tumour? 2. What is likely the behavior of the tumour? 3. What is the extent…

Differential Diagnosis in Dermatopathology

Pagetoid Bowen’s disease vs. Extramammary Paget’s disease

Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds. This disease has a predilection for intertriginous regions. The condition may develop consequent to…

Differential Diagnosis in Dermatopathology

Discussions

…er. There is but one authentic form of the disease, namely, an adenocarcinomatous process that originates in the epidermis. A simulator of extramammary Paget’s disease extends into the epidermis from a contiguous adenocarcinoma of the genitouri…