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A Clinical Atlas of 101 Common Skin Diseases

Alopecias

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Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role.

A Clinical Atlas of 101 Common Skin Diseases

Dermatofibroma

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An inflammatory process that develops secondary to trauma, usually in the form of a penetrating injury or rupture of a follicle, and that proceeds through stages of granulation tissue with numerous extravasated erythrocytes, granulomatous inflammation, and fibrosis.

A Clinical Atlas of 101 Common Skin Diseases

Dermatofibrosarcoma Protuberans

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A malignant nonepithelial neoplasm (a sarcoma) presumably of perineural fibrocytes that presents itself usually on the trunk, but sometimes elsewhere, such as the extremities, face, and scalp.

A Clinical Atlas of 101 Common Skin Diseases

Mycosis Fungoides

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A systemic lymphoma of T-lymphocytes that manifests itself first in the skin as macules and then patches that often are scaly.

A Clinical Atlas of 101 Common Skin Diseases

Neurofibromatosis

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A constellation of lesions that represent disorders of melanocytes (e.g., axillary "freckles" and café au lait "spots") and of proliferations of Schwann cells (e.g., papules, nodules, and tumors of neurofibroma).

A Clinical Atlas of 101 Common Skin Diseases

Pruritic Urticarial Papules and Plaques of Pregnancy

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An inflammatory process in pregnant women near term that consists of urticarial papules and plaques, especially on the trunk and particularly in association with lesions of striae atrophicantes, the lesions disappearing shortly after parturition.

A Clinical Atlas of 101 Common Skin Diseases

Mycosis Fungoides

A systemic lymphoma of T-lymphocytes that manifests itself first in the skin as macules and then patches that often are scaly. Most people with the disease have only scaly macules and patches for a lifetime, but some patients may develop papules, pl…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomas (Other Than Mycosis Fungoides and Lymphomatoid Papulosis)

…ties, and large B-cell lymphoma with predilection for the legs of older patients. Cutaneous T-cell lymphomas other than mycosis fungoides present themselves as macules and patches, papules and plaques, and nodules and tumors that may appear on any a…

Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides

…ties, and large B-cell lymphoma with predilection for the legs of older patients. Cutaneous T-cell lymphomas other than mycosis fungoides present themselves as macules and patches, papules and plaques, and nodules and tumors that may appear on any a…

Therapeutic Strategies in Dermatology

Alopecia

…ties, and large B-cell lymphoma with predilection for the legs of older patients. Cutaneous T-cell lymphomas other than mycosis fungoides present themselves as macules and patches, papules and plaques, and nodules and tumors that may appear on any a…

Therapeutic Strategies in Dermatology

Alopecia: Key Points

Key Points Alopecia, or hair loss, has a broad spectrum of causes. In order to appropriately treat alopecia, the type of hair loss or pathophysiology must be clearly identified. The evaluation for hair loss requires a very thorough history and phys…

Therapeutic Strategies in Dermatology

Alopecia: Treatment

Treatment First-line treatment strongly depends on the type of hair loss. Specific pharmacologic treatments are discussed below for the two most common causes of alopecia: androgenetic alopecia and alopecia areata. Ancillary therapy In all cases…

A Clinical Atlas of 101 Common Skin Diseases

Alopecias

Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role. Although the scalp is the site most often affected, any region of the skin that be…

Therapeutic Strategies in Dermatology

Alopecia: Clinical Cases

…llow-up evaluation Hair-pulling is ongoing, but several areas of prior alopecia now have full regrowth Reassurance is emphasized; continuation of family counseling is encouraged Case 2 16-year-old healthy boy with sudden onset of asymptomatic h…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…ail units, in each of which changes are induced by the effects of the products of neoplastic lymphocytes. Patches of mycosis fungoides, i.e., lesions of large-plaque parapsoriasis and small-plaque parapsoriasis, including alopecia mucinosa, do not ev…

Therapeutic Strategies in Dermatology

Alopecia: Initial Evaluation

Initial Evaluation Differential diagnosis Alopecia areata Androgenetic alopecia Traction alopecia Trichotillomania Anagen effluvium…

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