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Therapeutic Strategies in Dermatology

Acrodermatitis Enteropathica: Overview

Zinc Deficiency Zinc deficiency may be seen in infants (hereditary or acquired) or adults (acquired). Some breastfed infants, especially if born prematurely, may develop acrodermatitis enteropathica due to zinc deficiency in mother’s breast mi…

Therapeutic Strategies in Dermatology

Alopecia: Key Points

…llness (such as syphilis, thyroid disease, anemia, nutritional deficiency, vitamin D deficiency, iron deficiency, or due to shifts of hair from the growth phase to shedding phase, known as telogen effluvium) idiopathic (such as frontal fibrosing alop…

Histologic Diagnosis of Inflammatory Skin Diseases

a-1 antitrypsin deficiency

…electrophoretic 1 globulin pattern of serum in a1-antitrypsin deficiency. Scand J Clin Lab Invest 1963;15:132. Loche F, Tremeau-Martinage C, Laplanche G, Massip P, Bazex J. Panniculitis revealing qualitative alpha 1 antitrypsine deficiency (MS varia…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Treatment

…ization.  For severe disease, anti-tumor necrosis factor (TNF) alpha inhibitors can be highly effective and is supported by evidence. Of the available modalities, infliximab (5–8 mg/kg given weeks 0, 2, 6, 10, then every 6 to 8 weeks) is superior in…

Therapeutic Strategies in Dermatology

Psoriasis: Principles of Psoriasis Management

…treatment. Instruct the patient to wear protective glasses for 12 hours following psoralen ingestion. Specific forms: Systemic PUVA: Oral methoxypsoralen before UVA exposure. Bath PUVA: The patient bathes for 15-30 minutes in a diluted solution of p…

Therapeutic Strategies in Dermatology

Candidiasis: Initial Evaluation

…onychia Differential diagnosis Inverse pityriasis rosea Deficiency dermatitis (such as zinc deficiency, aka acrodermatitis enteropathica) Allergic or irritant contact dermatitis Inverse psoriasis Tinea cruris Extramammary Paget&#82…

Therapeutic Strategies in Dermatology

Alopecia: Clinical Cases

Clinical Cases Case 1 8-year-old healthy girl with a two-year history of hair loss Irregular, jagged and scattered patches of hair loss on the scalp; no eyelashes Parents note that hair loss started when the family moved to a new state and describe a difficult, ongoing transition to their new home Initial visit No biopsy […]

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…g system may be used: Stage I: Localized cutaneous (fewer than 10 lesions, or one anatomic region); Stage II: Disseminated cutaneous (more than 10 lesions, or more than one anatomic area); Stage III: Visceral only; Stage IV: Cutaneous and visceral or…

Therapeutic Strategies in Dermatology

Lymphomatoid Papulosis: Overview

Overview Lymphomatoid papulosis (LyP) is an inflammatory disorder affecting primarily the upper dermal blood vessels. It is characterized by the presence of CD30-positive lymphocytes (sometimes large and atypical) in the dermal infiltrate. Individua…

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