Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…monly presents as papules, plaques, lupus pernio, or scar- or tattoo-associated lesions. Introduction Sarcoidosis is a complex multisystem inflammatory disease characterized by noncaseating granulomatous inflammation. The vast majority of patients h…

Therapeutic Strategies in Dermatology

Sarcoidosis: Treatment

…d depth of lesion). Patients should be evaluated for scar- or tattoo-associated lesions; patients who have tattoo-associated lesions should be counseled to avoid more tattoos. Subsequent steps Patients who fail to respond to local therapy should be…

Therapeutic Strategies in Dermatology

Lichen Planus: Treatment

…planus have been reported in associated with dental mercurial amalgams or other dental prosthetics and likely reflect a hypersensitivity reaction. Individuals with recalcitrant lesions on the buccal mucosa in contact with amalgam dental work should b…

Therapeutic Strategies in Dermatology

Sarcoidosis: Clinical Case

…th. Detailed examination reveals a few scaly papules within a tattoo on the arm There is no lymphadenopathy or hepatosplenomegaly on exam The eyes appear red with conjunctival injection The patient has a dry, nonproductive cough occasionally evident…

Therapeutic Strategies in Dermatology

Vitiligo: Treatment

Treatment Localized disease, <5% body surface area First-line therapy: Topical treatment options include a mid- to superpotent topical steroid (such as betamethasone or clobetasol) applied twice daily to the skin. Evidence supports that this is…

Histologic Diagnosis of Inflammatory Skin Diseases


…in the dermis and in the wall of a muscle-containing vessel = Tattoo by silver Elastic fibers in the wall of a vessel also have been stained by silver in a manner analogous to that in amalgam tattoos and in argyria. 10.38.21A: Fibrosing dermati…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…bbed and scratched (Quiz #559) Alopecia Universalis (Quiz #7) Amalgam tattoo (Quiz #853) Anaplastic large-cell lymphoma (Quiz #389) Angiolymphoid hyperplasia with eosinophilia (Quiz #424) Angiosarcoma (Quiz #819) Annular erythema of infancy (Quiz #15…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Malignant Spitz Nevus?

…r metastasis to a regional lymph node only. All of this is an amalgam of malarkey, poppycock, humbug, balderdash, and just plain hogwash. Those who are advocates of the misguided concept of “atypical Spitz’s nevus” tend to be propon…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Colors Stereotypical for Diseases Specific?

…lesions are usually inflammatory, excepting in nevi, and red tattooing. Yellow and orange lesions are found in xanthoma, and the former in some of the papules in lupus vulgaris, and in other tubercular lesions, vesicles, pustules and in some crusts….

Dermatology Practical & Conceptual

Melanoma and satellite blue papule

…oma. Finally, exogenous dermal blue pigmentation, such as ink tattoo, radiation tattoo, and traumatic penetration of foreign pigmented materials. Our differential diagnosis for this blue lesion included CMM, common blue nevus and foreign body reactio…