Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

Key Points Sarcoidosis is a multisystem inflammatory disease, characterized by non-caseating granulomas, which occurs in patients of all ages and ethnic groups. Patients require thorough evaluation for multisystem disease and close monitoring for t…

Therapeutic Strategies in Dermatology

Sarcoidosis: Treatment

…nd depth of lesion). Patients should be evaluated for scar- or tattoo-associated lesions; patients who have tattoo-associated lesions should be counseled to avoid more tattoos. Subsequent steps Patients who fail to respond to local therapy should b…

Therapeutic Strategies in Dermatology

Lichen Planus: Treatment

…planus have been reported in associated with dental mercurial amalgams or other dental prosthetics and likely reflect a hypersensitivity reaction. Individuals with recalcitrant lesions on the buccal mucosa in contact with amalgam dental work should…

Therapeutic Strategies in Dermatology

Sarcoidosis: Clinical Case

Clinical Case Case 1 38-year-old African American man No significant past medical history Review of systems reveals a chronic persistent cough over the past 4-5 months, mild fatigue, with no ocular complaints, no palpitations, and no other syste…

Therapeutic Strategies in Dermatology

Vitiligo: Treatment

Treatment Localized disease, <5% body surface area First-line therapy: Topical treatment options include a mid- to superpotent topical steroid (such as betamethasone or clobetasol) applied twice daily to the skin. Evidence supports that this is…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…in the dermis and in the wall of a muscle-containing vessel = Tattoo by silver Elastic fibers in the wall of a vessel also have been stained by silver in a manner analogous to that in amalgam tattoos and in argyria. 10.38.21A: Fibrosing dermat…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…ubbed and scratched (Quiz #559) Alopecia Universalis (Quiz #7) Amalgam tattoo (Quiz #853) Anaplastic large-cell lymphoma (Quiz #389) Angiolymphoid hyperplasia with eosinophilia (Quiz #424) Angiosarcoma (Quiz #819) Annular erythema of infancy (Quiz #1…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Malignant Spitz Nevus?

“A rare malignant variant of the Spitz naevus has been reported which features a higher mitotic rate and subcutaneous invasion. It may metastasize to the regional lymph nodes but not beyond.” Weedon D, Stratton G. Malignant melanoma pa…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Colors Stereotypical for Diseases Specific?

“The color of skin lesions varies as already stated. … White lesions are rare excepting in exfoliative diseases, the scales of which are white. They usually result from loss of pigment. White spot disease, morphea, some of the idiopathi…

Dermatology Practical & Conceptual

Melanoma and satellite blue papule

…coma. Finally, exogenous dermal blue pigmentation, such as ink tattoo, radiation tattoo, and traumatic penetration of foreign pigmented materials. Our differential diagnosis for this blue lesion included CMM, common blue nevus and foreign body reacti…