A Clinical Atlas of 101 Common Skin Diseases

Amyloidosis

  • at006g01.jpg
  • at006g02.jpg
  • at006g03.jpg
  • at006g04.jpg
  • at006g05a.jpg
  • at006g05b.jpg
  • at006g06.jpg
  • at006g07.jpg
  • at006g08.jpg
  • at006g09.jpg

A condition in which deposits of a fibrillary protein (amyloid) appear in the skin as macules, papules, and nodules consequent to the effects of local factors, or as patches (which may be purpuric), plaques, nodules, and tumors as a result of a systemic disease like myeloma.

A Clinical Atlas of 101 Common Skin Diseases

Amyloidosis

A condition in which deposits of a fibrillary protein (amyloid) appear in the skin as macules, papules, and nodules consequent to the effects of local factors, or as patches (which may be purpuric), plaques, nodules, and tumors as a result of a syst…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…tive antigens include an unknown autoantigen, misfolded serum amyloid A proteins, infectious agents (including mycobacteria or Propionibacterium acnes), particulate matter, or heavy metals/dust/debris. Whatever the inciting exposure, these genetical…

Histologic Diagnosis of Inflammatory Skin Diseases

Macular and papular (lichenoid) amyloidosis-Cutaneous solely

Macular and papular (lichenoid) amyloidosis—Cutaneous solely Presentation stereotypical Age and sex Women of Asian, Latin, or Middle Eastern ancestry usually Distribution of lesions Macular form most common in the interscapular region, but also seen…

Differential Diagnosis in Dermatopathology

Lichen amyloidosis vs. Colloid milium

A condition in which deposits of a fibrillary protein (amyloid) appear in the skin as macules, papules, and nodules consequent to the effects of local factors, or as patches (which may be purpuric), plaques, nodules, and tumors as a result of a syst…

Differential Diagnosis in Dermatopathology

Discussions

Lichen amyloidosis and colloid milium both result from deposits of homogeneous material in the dermis, but the composition chemical of them is as different as the appearance of them histopathologically. In both conditions, fibrocytes are affiliated…

Dermatology Practical & Conceptual

Notalgia paresthetica: the unreachable itch

…ntact dermatitis, parapsoriasis, neurodermatitis, and macular amyloidosis. Biopsy of NP may show signs of post-inflammatory hyperpigmentation, mild hyperkeratosis, and mild inflammatory infiltrate of the papillary dermis with dermal melanophages [2,3…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Lichen amyloidosis Colloid milium 1. Surface scalloped 1. Surface domed 2. Foci of compact orthokeratosis associated with epidermal hyperplasia overlie globules of amyloid in the papillary dermis 2. Thinned epidermis with loss of the normal un…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…es in the papillary dermis + 11.3.1C + 11.3.1D = Amyloidosis, macular  The absence of any sign of lichen simplex chronicus indicates that this is a macular, rather than a papular, expression of amyloidosis. Scratching is thought to kill…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Hyalin?

…antile myofibromatosis. Am J Pathol 1994; 144:480-85. “Amyloid-hyaline-colloid deposition. Disorder: Amyloidoses Familial amyloidotic neuropathy ß2-Microglobulin amyloid Colloid milium Hyalinosis cutis et mucosae Porphyria Gout (tophi) Waldens…