Search Results for: apoptosis

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Apoptosis?

“… this distinctive type of necrosis (apoptosis)…has previously been called shrinkage necrosis on morphological grounds.” Kerr JFR. Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide ranging implication…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

APOPTOSIS [Gk. apo– (away from) + ptosis (a falling)]: Reputed to be a specific type of cell death in which dead cells are said to undergo fragmentation by implosion with subsequent phagocytosis of nuclear debris (Fig. 3.40). The process is cl…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…also of some collagen, is responsible for anetoderma. Error: Apoptosis is not necrosis. Reason: In classic Virchowian pathology, necrosis is characterized cytopathologically by three signs, namely, pyknosis, karyorrhexis, and karyolysis; apoptosis i…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

…tic keratocytes referred to as “apoptotic cells”; apoptosis, typified as it is by pyknosis and karyorrhexis, fulfills criteria for necrosis. Utilizing the five essential patterns of perivascular dermatitis and subdivisions of them, the fo…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…eet’s syndrome and bullous lupus erythematosus. Because apoptosis is characterized by karyorrhexis and pyknosis, it qualifies as a type of necrosis. Karyorrhexis of lymphocytes is common in the subcutaneous fat of lupus profundus and karyorrhex…