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Therapeutic Strategies in Dermatology

Palmar and Plantar Keratoderma: Overview

…lets, as well as sequential radiographic studies (to look for calcification of the ligaments and premature epiphysial closure). Some patients with PPK, treated with retinoids, develop severe skin fragility, which can make the patient more uncomfortab…

Therapeutic Strategies in Dermatology

Ichthyoses/Disorders of Cornification: Overview

…latelets, as well as sequential radiographic studies (to look for calcification of the ligaments and premature epiphysial closure). Retinoid therapy is best managed by a physician with special expertise in these applications at these high dosages….

Therapeutic Strategies in Dermatology

Chondrodermatitis Nodularis Helicis: Key Points

…alized tissue ischemia, either due to local vascular factors (arteriole narrowing), external pressure or trauma, or cold-induced vasospasm. Most patients to not recall a specific inciting trauma, but external factors likely play a role in the disease…

A Clinical Atlas of 101 Common Skin Diseases

Pyogenic Granuloma

…of small cutaneous vessels which are “fed” by an arteriole in the subcutaneous fat, the lesion resulting consistently from external trauma, usually in the form of a puncture or a yank of a “hang nail.” In time, the proliferat…

A Clinical Atlas of 101 Common Skin Diseases

Dermatomyositis

An inflammatory disease of children and adults that tends to involve skin and skeletal muscle mostly, the findings in the skin being patches with the color of heliotrope, especially in the periocular region. The disease manifests itself as poikilode…

A Clinical Atlas of 101 Common Skin Diseases

Cysts and Cystic Hamartomas

Papules, nodules, and tumors that, on gross examination, are usually skin colored and, on histopathologic examination, consist of an epithelium-lined sac that contains fluid, cells, or both in the case of true cysts and of cysts that are associated…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Subcutaneous Fat: Panniculitis

…eatic panniculitis, pictured here at a stage characterized by calcification (saponification) of adipocytes. Figure 5.388 A&B. Septal and lobular panniculitis concurrently: erythema nodosum. At times, both septa and lobules may be affected near…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…A: Vasculitis, small-vessel + 10.63.41B: A thrombus in an arteriole in the lower part of the dermis, abundant mucin in the dermis, and a perivascular and interstitial infiltrate of lymphocytes = Degos’ disease ¬†This still-evolving lesion of…

Histologic Diagnosis of Inflammatory Skin Diseases

Pancreatic panniculitis

…es similar to those in fully developed lesions plus: Striking calcification in fat lobules accompanied by fibroplasia, but not by fat necrosis or by neutrophils Ghosts of adipocytes outlined by calcium Correlation clinicopathologic Extensive necrosi…

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