Therapeutic Strategies in Dermatology

Vascular Birthmarks: Key Points

Key Points Vascular birthmarks are cutaneous vascular lesions present at, or shortly after, birth. They may be categorized as vascular tumors or vascular malformations. The term hemangioma has previously been used to describe many common, typicall…

A Clinical Atlas of 101 Common Skin Diseases

Hemangiomas, Vascular Malformations, and Ectasias

An hemangioma is a benign neoplasm of blood vessels, a vascular malformation is an aberration in development of one or more major vascular structures, and an ectasia is a dilation of a preexisting end vessel….

Histologic Diagnosis of Inflammatory Skin Diseases

Acroangiodermatitis of Mali/Stewart-Bluefarb syndrome

…of purple nodules on a limb as a consequence of an underlying arteriovenous malformation. Similar changes occur on upper limbs of patients on hemodialysis as a consequence of an arteriovenous fistula. Differential diagnosis clinical Kaposi’s…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…s in structure of blood vessels, such as a malformation (e.g., arteriovenous shunt), and an ectasia (e.g., Osler-Weber-Rendu syndrome). For these reasons, there is no need ever to employ the term vasculopathy; the particular pathologic process that i…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Angiolymphoid Hyperplasia with Eosinophilia/Kimura’s Disease?

…fundamentally is a manifestation of a malformation, to wit, an arteriovenous shunt seated in the subcutaneous fat or even deeper in the subcutis. Although expressions morphologic of angiolymphoid hyperplasia may involve the dermis alone, the subcutan…

Differential Diagnosis in Dermatopathology

Discussions

…a vascular malformation that comes into being by virtue of an arteriovenous shunt, angiosarcoma is a malignant neoplasm with blood vascular differentiation. Although clinically and biologically the two conditions are very different from one another,…

Differential Diagnosis in Dermatopathology

Angiolymphoid hyperplasia with eosinophilia vs. Angiosarcoma

An hemangioma is a benign neoplasm of blood vessels, a vascular malformation is an aberration in development of one or more major vascular structures, and an ectasia is a dilation of a preexisting end vessel….

Histologic Diagnosis of Inflammatory Skin Diseases

Nail Units

…highly vascular, especially in papillae. In addition, special arteriovenous shunts, known as Sucquet-Hoyer canals and lined by endothelial cells that, in turn, are rimmed by glomus cells, are present in the dermis. They help to regulate temperature…

Histologic Diagnosis of Inflammatory Skin Diseases

Blood Vessels

Blood vessels in the skin of an embryo come into being when mesenchymal cells arranged in an intricate network arborize and encircle conduits that are seen through a microscope as mere spaces. The dermal vasculature consists of a superficial and a d…

Differential Diagnosis in Dermatopathology

Discussions

For many years, authors of publications in English used the terms “Kimura’s disease” and “angiolymphoid hyperplasia with eosinophilia” as synonyms. In truth, these two diseases are different in nearly every respect and…