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Therapeutic Strategies in Dermatology

Melanoma: Treatment

…herapy: Surgical excision For diagnosis, complete excisional biopsy with minimal margins, pathologically evaluated at multiple levels to determine the tumor thickness, as well as to determine presence of ulceration, mitotic index, evidence of regres…

Therapeutic Strategies in Dermatology

Alopecia: Clinical Cases

…ult, ongoing transition to their new home Initial visit No biopsy is indicated; on further questioning, the parents admit that they have noticed their daughter pulling at her hair, especially the eyelashes, when stressed; a diagnosis of trichotill…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Clinical Cases

…ous, undermined border Diagnosis: pyoderma gangrenosum A skin biopsy to exclude infectious or other inflammatory etiology is declined by the patient Clobetasol ointment 0.05% applied daily under an occlusive hydrocolloid dressing is recommended Conce…

Therapeutic Strategies in Dermatology

Alopecia: Key Points

…valuation for hair loss may entail a hair sample mount, scalp biopsy, and/or blood tests to identify a diagnosis or underlying cause. There is not always an effective treatment for hair loss, but identifying the correct underlying process causing alo…

Therapeutic Strategies in Dermatology

Melanoma: Key Points

…sible signs of melanoma and warrant further evaluation and/or biopsy. Risk factors for melanoma include family history, atypical nevi, numerous nevi, genetic factors and UV exposure. The variation in size, depth (of invasion), color, and secondary ch…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…Skin lesions are an excellent source of diagnostic material. Biopsy the thickest nonulcerated lesion. Punch, excision, or shave biopsies (of exophytic nodules) are adequate. Do not biopsy at the edge of skin lesions, but rather in the center. Evalua…

Therapeutic Strategies in Dermatology

Lupus: Clinical Cases

…t Initial evaluation Diagnosis: Discoid lupus (confirmed by biopsy) Desonide 0.05% ointment b.i.d. (face) Clobetasol 0.05% ointment b.i.d. (scalp) Counseling on photoprotection and sun avoidance Vitamin D supplementation is recommended 4-week foll…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…fic lesions,” those that display characteristic granulomas on biopsy, and “sarcoid non-specific lesions,” which generally refers to erythema nodosum. Erythema nodosum (EN) is most often seen in patients of Northern European ancestry, presenting with…

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