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Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Clinical Cases

…including age-appropriate cancer screening, chest X-ray, and blood tests including complete blood count with differential, erythrocyte sedimentation rate, and rheumatologic serologies Follow-up in 1 week Follow-up evaluation The ulcer has not pro…

Therapeutic Strategies in Dermatology

Venous Stasis: Treatment

…spond after 48-72 hours, is febrile, or has an elevated white blood cell count, hospitalize the patient, culture the blood, and treat the patient with intravenous antibiotics to provide coverage for staphylococcal and streptococcal cellulitis. Subse…

Therapeutic Strategies in Dermatology

Urticaria: Clinical Cases

…pisodes since last clinic visit Escalate dose of fexofenadine Blood test: complete blood count with differential, ESR Follow-up evaluation at 4 weeks Follow-up evaluation at 4 weeks Patient reports ongoing improvement Blood test results show slight…

Therapeutic Strategies in Dermatology

Leukocytoclastic Vasculitis: Key Points

…cytoclastic vasculitis (LCV) represents inflammation of small vessels in the skin stemming from immune complex deposition. Clinically, LCV presents with an eruption of palpable monomorphous purpuric papules, which may have central vesicles or pustule…

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis): Clinical Cases

…including age-appropriate cancer screening, chest X-ray, and blood tests including complete blood count with differential, erythrocyte sedimentation rate, and rheumatologic serologies; given the absence of gastrointestinal symptoms, a colonoscopy to…

Therapeutic Strategies in Dermatology

Lymphomatoid Papulosis: Overview

…an inflammatory disorder affecting primarily the upper dermal blood vessels. It is characterized by the presence of CD30-positive lymphocytes (sometimes large and atypical) in the dermal infiltrate. Individual lesions resolve spontaneously (albeit ov…

Therapeutic Strategies in Dermatology

Livedo Vasculitis/Livedo Reticularis/Atrophie Blanche: Overview

…hypercoagulable tendency. Histology will reveal thrombosis of vessels without inflammation. Therapeutic strategy is aimed at treating the prothrombotic state. The ulcerations will heal when the primary hypercoagulable state has been addressed. The th…

Therapeutic Strategies in Dermatology

Alopecia: Key Points

…air loss may entail a hair sample mount, scalp biopsy, and/or blood tests to identify a diagnosis or underlying cause. There is not always an effective treatment for hair loss, but identifying the correct underlying process causing alopecia enables c…

Therapeutic Strategies in Dermatology

Vascular Birthmarks: Key Points

…of endothelial cells (staining GLUT-1 positive on biopsy) and blood, without organized blood flow. In most cases, HOI represent asymptomatic benign lesions that do not require immediate intervention; options for later treatment may involve laser-assi…

Therapeutic Strategies in Dermatology

Erysipelas/Cellulitis: Clinical Cases

…emperature 38.5 degrees Celsius, other vital signs are stable Blood work reveals a marked leukocytosis Admit to hospital for intravenous antibiotics (nafcillin) Next day After one day of treatment, he defervesced, and clinical signs of erythema and…

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