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Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Key Points

…cella zoster virus (VZV). Herpes zoster (shingles) represents activation of varicella zoster virus from cranial or dorsal root ganglion, thus affecting the skin in a dermatomal distribution. It can disseminate and can have internal organ involvement….

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…a Langerhans cell that has been arrested at an early stage of activation and is functionally deficient. This disorder is classified as single-system disease, multisystem disease, or multisystem disease with organ dysfunction. The skin is one of the m…

Therapeutic Strategies in Dermatology

Urticaria: Initial Evaluation

…ding to antigens or through direct (non-IgE, non-immunologic) activation (by radiocontrast dye, NSAIDs, opiates, general anesthetics). This immune cell degranulation results in release of many immunologic mediators such as histamine (resulting in vas…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…th active sarcoidosis often have granuloma-mediated vitamin D activation and increased levels of 1,25 dihydroxy-vitamin D. They may develop hypercalcemia, and the presence of persistent hypercalcemia and subsequent hypercalciuria can damage the kidne…

Therapeutic Strategies in Dermatology

Granuloma Annulare: Key Points

…deposition—may trigger a reactive inflammatory response; this hypothesis has been suggested for similar reactive granulomatous processes in the skin (such as palisaded neutrophilic and granulomatous dermatitis or interstitial granulomatous dermatitis…

Therapeutic Strategies in Dermatology

Rosacea: Treatment

Subtypes of rosacea and their treatments Erythemato-telangiectatic (E-T) subtype Patients often complain of intolerance or sensitivity to topical products and cosmetics. This subtype is best treated with avoidance of flushing, photoprotection, and…

A Clinical Atlas of 101 Common Skin Diseases

Dermatitis Herpetiformis

An inflammatory process characterized by symmetrical distribution, especially on the skin of the scalp, overlying the scapulae and the sacrum, on the buttocks, and on the extensor surface of the extremities, of clusters of urticarial papules, papulo…

A Clinical Atlas of 101 Common Skin Diseases

Dyshidrotic Dermatitis

A pruritic papular and vesicular inflammatory process of unknown cause that tends to affect the sides of fingers and toes, as well as palms and soles. The name “dyshidrotic” is misleading; the condition has no relation whatever to eccrin…

A Clinical Atlas of 101 Common Skin Diseases

Dermatofibrosarcoma Protuberans

A malignant nonepithelial neoplasm (a sarcoma) presumably of perineural fibrocytes that presents itself usually on the trunk, but sometimes elsewhere, such as the extremities, face, and scalp. A papule of it tends to become a plaque, a nodule, a tum…

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