Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Overview

…ion once daily. These agents are in alcohol vehicles and will burn if there is extensive fissuring of the lesions. Immediately after application of astringent, apply clindamycin 1% solution. Mupirocin is in an ointment base and is less acceptable in…

A Clinical Atlas of 101 Common Skin Diseases

Phototoxic Dermatitis

…d systemically in combination with the effects of ultraviolet light, the result being a caricature of sunburn. The lesions consist of erythema and blisters, some of which may be large bullae, and occur on sites exposed directly to ultraviolet light….

Histologic Diagnosis of Inflammatory Skin Diseases

Burns

Burns Synonyms Thermal injuries Presentation stereotypical Age and sex Any age and both sexes Distribution of lesions Regions that usually are exposed rather than covered Configuration of lesions Depends on the particular type of burn; bizarre shape…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…looned keratocytes and confluent epidermal necrosis = Thermal burn This is not a true dermatitis because there is no infiltrate of inflammatory cells. It is a first-degree burn because the changes are confined to the epidermis. That the lesion develo…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Degeneration Syndrome?

…and a normal cornified layer. LoPresti et al. believed that a burn by the hot petrolatum was responsible for the alopecia. The findings histopathologic in hot-comb alopecia, described and presented in photomicrographs by LoPresti et al., are not thos…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…tes and a sparse perivascular infiltrate of lymphocytes = Any burn, including sunburn/phototoxic dermatitis     Broad Zone of Parakeratosis Containing Neutrophils Neutrophils, or remnants of them (nuclear “dust”), disp…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…#229) Bullous pemphigoid, vesiculo-bullous stage (Quiz #230) Burn, first-degree, repeated countless times for many years (erythema ab igne) (Quiz #347) Burn, second-degree, consequent to contact repeatedly with a hot grill for many months (erythema…

Dermatology Practical & Conceptual

A reticulated pigmented rash on the lower leg

…the range 45-470 C, which is usually insufficient to cause a burn. In rural areas of the world, the lesion is traditionally caused by sitting or cooking near an open fire. Laptops are becoming one of the most frequent causes of this entity in the in…

Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…Hypertrophic scar Atrophic scar Hypertrophic scars, such as burn scars, albopapuloid lesions of dystrophic epidermolysis bullosa, and conventional scars that follow surgical incisions Atrophic scars, such as those of macular atrophy in acne vulgari…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

…21; sustained instantly, no matter how severe, such as from a burn of any kind, the damage occurring rapidly and the effects of it thereby taking a toll only on cells that are viable. Figure 5.171 A&B. A distinctive sign of injury from outside…