Therapeutic Strategies in Dermatology

Photosensitivity Dermatoses: Overview

Photosensitive drug eruptions, polymorphous light eruption, chronic actinic dermatitis (CAD -includes the conditions previously called photosensitive eczema, actinic reticuloid and persistent light reaction). Photosensitivity dermatoses are caused e…

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…ite Sarcoptes scabiei, when acute, is typified clinically by a burrow, i.e., a tunnel, clinically sometimes slightly curved, in the stratum corneum with a vesicle often at the far end of it; at other times, the entire length of the intraepidermal bur…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.5.1A: Perivascular and interstitial dermatitis + 10.5.1B: Lymphocytes and eosinophils around venules, and neutrophils in the interstitium in conjunction with degeneration of bundles of collagen focally = Response to an arthropod…

Dermatology Practical & Conceptual

Pre-emptive diagnosis of a case of scabies by dermatopathology

Case presentation A 39-year-old woman reported to her general practitioner with a new pigmented skin lesion on her right pectoral region (Figure 1). Dermatoscopically there were no suspicious features and the decision was made to monitor it over a t…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…

Differential Diagnosis in Dermatopathology

Discussions

Nodular scabies and lymphomatoid papulosis have many attributes histopathologic in common. Both consist of infiltrates whose pattern is superficial and deep, perivascular, and interstitial, and whose population of cells may be mixed, i.e., small lym…