Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Key Points

Dermatitis herpetiformis (DH) is an intensely pruritic, chronic disorder characterized by symmetrically distributed papulovesicles, bullae, or erosions. DH is an autoimmune blistering disease that is a cutaneous manifestation of gluten sensitivity….

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Clinical Case

Case 1 35-year-old female No past medical history Family history notable for celiac disease Presents for evaluation and management of new, intensely pruritic eruption on elbows, lower back, hips, buttocks, posterior thighs. Prior treatments with…

Therapeutic Strategies in Dermatology

Erythema Elevatum Diutinum: Key Points

Erythema elevatum diutinum (EED) is a rare chronic form of fibrosing vasculitis. Firm, red to brown or violaceous nodular lesions developing over joints of the elbows, knees, hands, and feet, often in a symmetric pattern, is the hallmark cutaneous…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Treatment

First-line therapy: ┬áThe first-line therapy for DH is oral dapsone once each day (100 mg daily dose). Dapsone should be started after G6PD screening is performed. A dramatic clinical response is expected within 4-5 days. Reevaluate the patient afte…

Therapeutic Strategies in Dermatology

Erythema Elevatum Diutinum: Treatment

First-line therapy: The first-line therapy for EED is oral dapsone once each day (50-100 mg daily dose). Alternative steps Intralesional triamcinolone acetonide 2.5-5 mg/cc may be used if there are few lesions. Niacinamide, colchicine, hydroxychlor…

A Clinical Atlas of 101 Common Skin Diseases

Dermatitis Herpetiformis

An inflammatory process characterized by symmetrical distribution, especially on the skin of the scalp, overlying the scapulae and the sacrum, on the buttocks, and on the extensor surface of the extremities, of clusters of urticarial papules, papulo…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermatitis herpetiformis

Dermatitis herpetiformis Synonyms During-Brocq disease Duhring’s disease Presentation stereotypical Age and sex Begins usually in young adults, but may appear for the first time in children or in middle-aged persons; no predilection for eith…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus Versus Systemic Lupus Erythematosus?* I

*This subject was addressed in Resolving Quandaries I. Because the quandary was not resolved to our satisfaction there, it is revisited here. “Discoid lupus lesions can occur as the sole manifestation of lupus in the absence of systemic di…