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A Clinical Atlas of 101 Common Skin Diseases

Keratosis Pilaris/Lichen Spinulosus

Keratotic spikes that emerge from dilated ostia of infundibula and are equidistant from one another. The term keratosis pilaris refers to the phenomenon when it presents itself without any distinct arrangement of individual lesions, whereas the desi…

A Clinical Atlas of 101 Common Skin Diseases

Acne Vulgaris

A disease of infundibulosebaceous units, especially infundibula, that may manifest itself solely as noninflammatory lesions, i.e., comedones and intact cysts, or as inflammatory lesions, i.e., papules, nodules, and pustules. The process may resolve…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eccrine, Apocrine, and Apoeccrine Sweat Glands?

…8220;pinched off,” a phenomenon that has earned apocrine secretion the synonymous designation “decapitation secretion.” Apocrine glands are not distributed universally in the skin, they being found only at certain sites, namely, the…

Histologic Diagnosis of Inflammatory Skin Diseases

Apocrine Units

…portion of glandular cells shows changes specific for apocrine secretion, namely, the appearance of being decapitated or pinched off (Fig. 1.52). “Decapitation secretion,” “pinching-off secretion,” “snouts,” and &#…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Breast a Sweat Gland?

…dramatically in the form of caricature of “decapitation secretion” of the epithelial cells that line them. Decapitation secretion, known also as “pinching-off secretion,” is the sine qua non for identification of the apocrine…

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

All constituents of human skin are derived from either ectoderm or mesoderm. The epithelial structures, i.e., epidermis (surface and infundibular), apocrine units, sebaceous units, hair follicles, eccrine units, and nail units, come from ectoderm. M…

Histologic Diagnosis of Inflammatory Skin Diseases

Sebaceous Units

…lipid and cellular debris known, in conglomerate, as sebaceous secretion. After discharge of that secretion into a duct and during its passage through the infundibulum to the skin surface, it carries with it normal flora of bacteria, yeasts, and mite…

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