Differential Diagnosis in Dermatopathology

Discussions

In a collagenous type of connective tissue nevus, known also as collagenoma, and in a lesion late in the course of morphea, abnormalities of connective tissue are observed mostly in the dermis. Bundles of collagen are thickened throughout the reticu…

Differential Diagnosis in Dermatopathology

Study By Disease

…us” (Masson’s blue neuronevus) (Quiz #359) “Collagenous” nevus, papillary dermal type* (Quiz #111) “Collagenous” nevus, papillary dermal type* (Quiz #441) “Collagenous” nevus, papillary dermal type* (Qu…

Histologic Diagnosis of Inflammatory Skin Diseases

Polymorphous light eruption

…ted, albeit tenuously, to the epidermis. Only when those fine collagenous connections to the epidermis have been broken can a subepidermal blister be said to have formed. Contrary to our thinking two decades ago about findings histopathologic in poly…

Histologic Diagnosis of Inflammatory Skin Diseases

Collagen

…t of the elastic fibril pictured, the latter consisting of noncollagenous microfibrils embedded in homogenous elastin. (x55,000) (Courtesy of Richard Wood, Ph.D.) Type II collagen is found in cartilage. Type IV collagen is a constituent of basement m…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nevus?

…mal nevi), of elements of connective tissue mostly, (e.g., in collagenous nevi, nevus flammeus, and nevus lipomatosus), and of a mixture of elements epithelial and nonepithelial (e.g., in nevus sebaceus). In each of the examples cited, nevus pertains…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Hyalin?

…acellular hyalin has been somewhat more difficult to analyze. Collagenous fibrous tissue in old scars may appear hyalinized … In long-standing hypertension and diabetes mellitus, the walls of arterioles, especially in the kidney, become hyalinized …W…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Chondrodermatitis Nodularis Helicis?

…ic evidence of perichondritis and degenerative changes of the collagenous tissue.” Mehregan AH, Hashimoto K, Mehregan DA, et al. Pinkus’ Guide to Dermatohistopathology, 6th ed. Norwalk, CT: Appleton & Lange, 1995:263. “The les…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…agen in the lower part of it. Much of the subcutaneous fat has been replaced by collagen bundles of character similar. In short, what is termed hypodermitis sclerodermiformis seems to be a consequence collagenous of the effects of severe stasis….