Search Results for: collarettes of epithelium

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A Clinical Atlas of 101 Common Skin Diseases

Dermatofibroma

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An inflammatory process that develops secondary to trauma, usually in the form of a penetrating injury or rupture of a follicle, and that proceeds through stages of granulation tissue with numerous extravasated erythrocytes, granulomatous inflammation, and fibrosis.

A Clinical Atlas of 101 Common Skin Diseases

Dermatofibrosarcoma Protuberans

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A malignant nonepithelial neoplasm (a sarcoma) presumably of perineural fibrocytes that presents itself usually on the trunk, but sometimes elsewhere, such as the extremities, face, and scalp.

A Clinical Atlas of 101 Common Skin Diseases

Neurofibromatosis

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A constellation of lesions that represent disorders of melanocytes (e.g., axillary “freckles” and café au lait “spots”) and of proliferations of Schwann cells (e.g., papules, nodules, and tumors of neurofibroma).

A Clinical Atlas of 101 Common Skin Diseases

Pruritic Urticarial Papules and Plaques of Pregnancy

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An inflammatory process in pregnant women near term that consists of urticarial papules and plaques, especially on the trunk and particularly in association with lesions of striae atrophicantes, the lesions disappearing shortly after parturition.

A Clinical Atlas of 101 Common Skin Diseases

Cysts and Cystic Hamartomas

…nodules, and tumors that, on gross examination, are usually skin colored and, on histopathologic examination, consist of an epithelium-lined sac that contains fluid, cells, or both in the case of true cysts and of cysts that are associated with…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Initial Evaluation

…s for PV should be referred to a dermatologist for a skin biopsy. The diagnosis of PV is made via biopsy of lesional skin or epithelium for H&E, and perilesional epithelium for DIF. The latter demonstrates IgG in an intercellular “chicken wire”…

A Clinical Atlas of 101 Common Skin Diseases

Molluscum Contagiosum

A hyperplasia of infundibular epithelium consequent to the effects of infection by a pox virus and manifesting itself clinically as one or more skin-colored, smooth-surfaced, dome-shaped papules, each with a central umbilication filled with horny…

A Clinical Atlas of 101 Common Skin Diseases

Extramammary Paget’s Disease and Mammary Paget’s Disease

Extramammary Paget’s disease is an apocrine carcinoma that begins within the epidermis and presents itself clinically as a patch or a subtle plaque that extends centrifugally for many years before becoming a readily discernible thick plaque,…

A Clinical Atlas of 101 Common Skin Diseases

Mammary Paget’s

Mammary Paget’s disease is an apocrine carcinoma that begins in mammary glands and extends along lactiferous ducts to the epidermis where it is seen clinically as a scaly, crusted, or eroded plaque on the nipple or areola of women mostly, and…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Key Points

…be deposition of IgG along the dermoepidermal junction (linear or granular pattern) not seen with PV. Additionally, indirect immunofluorescence demonstrates autoantibodies that bind to rat bladder epithelium in vitro….

A Clinical Atlas of 101 Common Skin Diseases

Pityriasis Rosea

An inflammatory process characterized by oval lesions marked at the periphery by collarettes of scale and distributed usually along lines of cleavage on the trunk especially, but in a general range from “the neck to the knees.”

A Clinical Atlas of 101 Common Skin Diseases

Erythema Annulare Centrifugum

An inflammatory disease characterized by lesions with arcuate, annular, and serpiginous outlines and by collarettes of scale on the inner margin of lesions that extend outward in centrifugal fashion, disappearing in months as a rule in the absence…

Histologic Diagnosis of Inflammatory Skin Diseases

Nail Units

…ressing around, behind, and under the nail to the distal edge, they are (1) the epidermis of the proximal nail fold, (2) the epithelium of the nail matrix, (3) the epithelium of the nail bed, (4) the epidermis of the hyponychium, and (5) the…

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

…e tissue, i.e., dermal papillae, fit into hollows on the undersurface of the epidermis. The follicle, but not the epidermis, epithelium of the nail unit, or epithelium of eccrine glands, is typified at its base by a discrete aggregation of…

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