Differential Diagnosis in Dermatopathology

Discussions

…ible for the formation of amyloid in lichen amyloidosis and of colloid in colloid milium. Because of the highly characteristic attributes histopathologic conditions, just listed, specialized stains need not be performed routinely to differentiate bet…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…ete ridges 5. Amyloid situated in widened dermal papillae 5. Colloid positioned in the upper half of the reticular dermis 6. Amyloid deposited as small globules 6. Colloid deposited as large homogeneous accumulations 7. Amyloid is amphophilic o…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…of which affect profoundly collagen and blood vessels). Error: Colloid is a distinct and distinctive substance. Reason: Colloid is nothing other than elastotic material that appears by conventional microscopy to be “homogenized.” Error: C…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Apoptosis?

“… this distinctive type of necrosis (apoptosis)…has previously been called shrinkage necrosis on morphological grounds.” Kerr JFR. Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide ranging implicatio…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Hyalin?

“With the high power the hyaline is seen in very varied forms, which all show the same fuchsin red reaction. The first forms a section by itself; it comprises hyaline balls of different size, which lie free between the epithelial cells, and w…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

APOPTOSIS [Gk. apo- (away from) + ptosis (a falling)]: Reputed to be a specific type of cell death in which dead cells are said to undergo fragmentation by implosion with subsequent phagocytosis of nuclear debris (Fig. 3.40). The process is claimed…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…