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A Clinical Atlas of 101 Common Skin Diseases

Syphilis

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An inflammatory process, caused by the spirochete Treponema pallidum, that tends to evolve through three stages, namely, primary (typified usually by a solitary chancre), secondary (characterized by widespread macules and papules on skin and mucous membranes in conjunction with signs and symptoms of systemic disease), and tertiary (manifested by gummas in the skin and destructive lesions also in the bones, eyes, brain, and elsewhere, resulting in debilitation and often death).

A Clinical Atlas of 101 Common Skin Diseases

Syphilis

An inflammatory process, caused by the spirochete Treponema pallidum, that tends to evolve through three stages, namely, primary (typified usually by a solitary chancre), secondary (characterized by widespread macules and papules on skin and mucous…

Therapeutic Strategies in Dermatology

Syphilis (Lues)

An inflammatory process, caused by the spirochete Treponema pallidum, that tends to evolve through three stages, namely, primary (typified usually by a solitary chancre), secondary (characterized by widespread macules and papules on skin and mucous…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Key Points

…f syphilis can be distinguished: primary, secondary, or early syphilis of less than 1 year’s duration; infection of indeterminate length, or more than 1 year’s duration; neurosyphilis; congenital syphilis; and syphilis infection in associ…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Treatment

…ely treat the fetus.Give additional penicillin therapy as for congenital syphilis (see below) to the baby at birth. 3, 6, 9, 12 and 24 months Indeterminate length, > 1 year duration Intramuscular benzathine penicillin G 2.4 x 106 U weekly for 3…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Initial Evaluation

Initial Evaluation Primary syphilis Secondary syphilis Tertiary syphilis Congenital syphilis Differential diagnosis Differential diagnosis of primary syphilis Herpes simplex virus Differ…

A Clinical Atlas of 101 Common Skin Diseases

Melanocytic Nevi and Melanotic Macules

Hamartomas (“congenital” melanocytic nevi) and benign neoplasms (“acquired” melanocytic nevi) of various specific types, all of which are composed of abnormal melanocytes and manifested clinically as lesions of different colo…

Therapeutic Strategies in Dermatology

Balanitis: Overview

…se, psoriasis, lichen planus, lichen sclerosis et atrophicus, syphilis, and scabies) may affect the glans penis preferentially. A total skin examination to rule out these other conditions should be performed. Any area of balanitis not responding to c…

Therapeutic Strategies in Dermatology

Syphilis (Lues): References

…ces http://www.cdc.gov/std/treatment/2010/genital-ulcers.htm#congenital Read PJ and Donovan B (2012) Clinical aspects of adult syphilis, Int Med Journal, 42: 614-619. Mattei, PL et al (2012) Syphilis: an emerging infection, AFP, 86: 433-440. Roett M…

Therapeutic Strategies in Dermatology

Viral Exanthems: Initial Evaluation

…t with a possible viral exanthem. Secondary syphilis, caused by the spirochete bacterium Treponema pallidum, results in a generalized eruption with scaly erythematous papules, characteristically with palmo-plantar involvement. Addit…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Clinical Cases

…performed (normal). Notably, no additional cutaneous signs of syphilis are found. A detailed sexual history is performed and his case (and contacts) are reported to the public health department. The patient is given an intramuscular dose of penicilli…

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