Histologic Diagnosis of Inflammatory Skin Diseases

Disseminated intravascular coagulopathy

Disseminated intravascular coagulopathy Synonyms Disseminated intravascular coagulation Presentation stereotypical Age and sex Usually adults of both sexes, but sometimes children Distribution of lesions Extremities especially Individual lesions Hem…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Subcutaneous Fat: Panniculitis

…rich in neutrophils conveys probability of septic vasculitis. Consumptive coagulopathy is a vaso-occlusive disease, not a vasculitis, just as amyloidosis, when systemic, is a vaso-intrusive disease, not a vasculitis; neither consumptive coagulopathy

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…vasculitis or a disease characterized by vaso-occlusion (e.g., consumptive coagulopathy) or vaso-intrusion (e.g., systemic amyloidosis). In theory, the term vasculopathy is applicable equally to increase in number of vessels in a proliferation of the…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vasculitis

…diseases absent an infiltrate of inflammatory cells, such as a consumptive coagulopathy or a dysgammaglobulinemia, and vasointrusive diseases devoid of inflammatory cells, such as is the case for systemic amyloidosis and calciphylaxis, are not true v…

Dermatology Practical & Conceptual

Tufted hemangioma: clinical case and literature review

…hemangioma. Subsequent activation of the thrombocytes leads to coagulopathy. Large hemangiomas may lead to congestive heart failure [7]. Osio et al. described a clinical variant of tufted hemangiomas with chronic coagulopathy, but without thrombocyto…

Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

The algorithmic method proposed in these pages and predicated on patterns histopathologic is intended to be more than just a guide to diagnosis of particular pathologic processes in skin and subcutaneous fat; it is meant to serve as a springboard fo…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Differential Diagnosis in Dermatopathology

Discussions

Leukocytoclastic vasculitis and livedo vasculitis, as their names denote, are vasculitides that favor the lower extremities, but whereas only the legs are affected as a rule in livedo vasculitis, any anatomic site may be involved by leukocytoclastic…