Histologic Diagnosis of Inflammatory Skin Diseases

Disseminated intravascular coagulopathy

Disseminated intravascular coagulopathy Synonyms Disseminated intravascular coagulation Presentation stereotypical Age and sex Usually adults of both sexes, but sometimes children Distribution of lesions Extremities especially Individual lesions Hem…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Subcutaneous Fat: Panniculitis

…any accompanying infiltrate of inflammatory cells, indicates consumptive coagulopathy, such as is seen in purpura fulminans, whereas thrombi in small vessels in company with an infiltrate rich in neutrophils conveys probability of septic vasculitis….

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vasculitis

…iseases absent an infiltrate of inflammatory cells, such as a consumptive coagulopathy or a dysgammaglobulinemia, and vasointrusive diseases devoid of inflammatory cells, such as is the case for systemic amyloidosis and calciphylaxis, are not true va…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…asculitis or a disease characterized by vaso-occlusion (e.g., consumptive coagulopathy) or vaso-intrusion (e.g., systemic amyloidosis). In theory, the term vasculopathy is applicable equally to increase in number of vessels in a proliferation of them…

Dermatology Practical & Conceptual

Tufted hemangioma: clinical case and literature review

…f patients may develop thrombocytopenia. Thrombocytopenia and coagulopathy in patients with tufted hemangiomas and kaposiform hemangioendotheliomas (known as Kasabach-Merritt syndrome) may be a grave consequence of both conditions. The phenomenon is…

Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

…ive diseases (ones typified by occlusion of a lumen), such as consumptive coagulopathies, as exemplified by purpura fulminans, and vaso-intrusive diseases (ones characterized by a deposit in the wall of the vessel), such as that which occurs when amy…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…lar purpura, thrombocytopenia, and disseminated intravascular coagulopathy. Figure 3.29 Purpura: petechiae and ecchymoses. PUSTULE [L. pustula (a small sore discharging pus)]: Clinically, an elevated, circumscribed collection of pus (neutrophils a…