Histologic Diagnosis of Inflammatory Skin Diseases

Thrombophlebitis

Thrombophlebitis Presentation stereotypical Age and sex Women most commonly Distribution of lesions Localized to the lower extremities usually Arrangement of lesions Linear often, i.e., along the course of a vein Individual lesions Cord sometimes in…

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

All constituents of human skin are derived from either ectoderm or mesoderm. The epithelial structures, i.e., epidermis (surface and infundibular), apocrine units, sebaceous units, hair follicles, eccrine units, and nail units, come from ectoderm. M…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

Morphologic and qualitative differences in hair, a cornified end-product of matrical cells positioned in the center of a follicular bulb, exist among the races of Man. In general, Caucasians have the most prominent hair, Asians have the least, and A…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Myxoma?

“myxoma (milk – s ? m?) [myxo – + G. -oma, tumor]. A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primiti…

Histologic Diagnosis of Inflammatory Skin Diseases

Interstitial granulomatous dermatitis with arthritis

Interstitial granulomatous dermatitis with arthritis Synonyms Interstitial granulomatous dermatitis with cutaneous cords and arthritis Rheumatoid papules Palisaded and neutrophilic granulomatous dermatitis Presentation stereotypical Age and sex Ad…

Differential Diagnosis in Dermatopathology

Discussions

Interstitial granulomatous dermatitis with arthritis, a distinctive disease that appears usually in patients with rheumatoid-like arthritis, has many attributes in common with the mostly interstitial type of granuloma annulare. Lesions of both condi…