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A Clinical Atlas of 101 Common Skin Diseases

Histiocytosis X

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A proliferation of abnormal Langerhans’ cells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that may be localized (to the vulva, for example) or widespread.

A Clinical Atlas of 101 Common Skin Diseases

Histiocytosis X

A proliferation of abnormal Langerhans’ cells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that m…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses

A proliferation of abnormal Langerhans’ cells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that m…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…e and graft vs. host disease may closely mimic Langerhans cell histiocytosis. In Langerhans cell histiocytosis, most patients are immunologically normal prior to therapy when evaluated by standard tests. Morbidity and mortality may be reduced by appr…

Histologic Diagnosis of Inflammatory Skin Diseases

Histiocytosis X

Histiocytosis X Presentation stereotypical Age and sex Children, boys mostly, and also adults Distribution of lesions Localized or widespread Individual lesions Red papules, purpuric papules, erosions, and ulcers Course Protracted, if not treated; s…

Therapeutic Strategies in Dermatology

Candidiasis: Key Points

Key Points Candidiasis typically affects mucosal sites and moist and/or occluded areas of skin: groin, axilla, inframammary, infra-abdominal pannus, glans penis (in uncircumcised males), and orogenital mucosal sites. Predisposing factors include o…

Therapeutic Strategies in Dermatology

Candidiasis: Treatment

Treatment First-line therapy: The first-line therapy should be specified for the affected anatomic site. Skin Initial therapy If the skin is macerated (e.g., moist, weeping), instruct the patient to soak in (or make an applied compress of) dilute…

Dermatology Practical & Conceptual

Langerhans cell histiocytosis-a case report

…fy it [10]. References 1. Crooks B, Grenier D. Langerhans cell histiocytosis: A complex recurrent disease. Paediatr Child Health. 2010;15(2): 69-70. 2. Abla O, Egeler RM, Weitzman S. Langerhans cell histiocytosis: current concepts and treatments. Can…

Differential Diagnosis in Dermatopathology

Mycosis fungoides, plaque vs. Histiocytosis X, plaque

A proliferation of abnormal Langerhans’ cells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that m…

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