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Therapeutic Strategies in Dermatology

Melanoma: Key Points

…ulceration, regression, mitotic index), by the location of the tumor, by the presence of regional or distant metastases, and by the patient characteristics (age, medical co-morbidities). Increased tumor thickness is associated with significant morbid…

Therapeutic Strategies in Dermatology

Vascular Birthmarks: Key Points

…benign vascular birthmarks that present in infancy with a wide spectrum of clinical presentations. Recent changes in the classification now restrict the term hemangioma to describe hemangioma of infancy, a benign, self-involuting, endothelial tumor t…

Therapeutic Strategies in Dermatology

Melanoma: Principles of Management of Melanoma

…ary melanoma (depth of invasion and/or the degree to which the tumor has invaded the skin, as well as ulceration and mitotic index). The major independent risk factor is tumor thickness measured in millimeters (Breslow depth). Depth of invasion is al…

Therapeutic Strategies in Dermatology

Psoriasis: Principles of Psoriasis Management

…lopment of a new class of drugs, engineered proteins targeting specific immunologic mediators involved in psoriasis, including tumor necrosis factor alpha (TNF-A), may offer effective treatments with fewer side effects than the more broadly acting im…

Therapeutic Strategies in Dermatology

Melanoma: Treatment

…commended. Recommended excision margins vary; no international standards yet exist (see Table 3). Table 3. Tumor thickness Recommended excision margins: United States Recommended excision margins: European (Leiter U, et al. 2010) Melanoma in si…

A Clinical Atlas of 101 Common Skin Diseases

Melanoma

…melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly shades of brown. A patch may become a plaque or upon it may develop a papule, nodule, or tumor. A papule may develop into a nod…

Differential Diagnosis in Dermatopathology

Apocrine mixed tumor vs. Eccrine mixed tumor

…melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly shades of brown. A patch may become a plaque or upon it may develop a papule, nodule, or tumor. A papule may develop into a nod…

Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease: Overview

Overview The diagnosis of Paget’s disease or extramammary Paget’s is made when Paget cells are identified in histopathologic specimens from involved skin. The term Paget’s disease is used when the cutaneous lesion is identified inv…

Therapeutic Strategies in Dermatology

Folliculitis (including pseudofolliculitis barbae): Key Points

…aureus. Gram-negative forms occur, usually on the face, in the setting of chronic, broad-spectrum antibiotic therapy of acne vulgaris. Since inflammation is limited to the hair follicle, classic signs of infection (dolor, calor, rubor, and tumor) may…

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