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Therapeutic Strategies in Dermatology

Melanoma: Key Points

…ulceration, regression, mitotic index), by the location of the tumor, by the presence of regional or distant metastases, and by the patient characteristics (age, medical co-morbidities). Increased tumor thickness is associated with significant morbid…

Therapeutic Strategies in Dermatology

Vascular Birthmarks: Key Points

…benign vascular birthmarks that present in infancy with a wide spectrum of clinical presentations. Recent changes in the classification now restrict the term hemangioma to describe hemangioma of infancy, a benign, self-involuting, endothelial tumor t…

Therapeutic Strategies in Dermatology

Psoriasis: Principles of Psoriasis Management

…lopment of a new class of drugs, engineered proteins targeting specific immunologic mediators involved in psoriasis, including tumor necrosis factor alpha (TNF-A), may offer effective treatments with fewer side effects than the more broadly acting im…

Therapeutic Strategies in Dermatology

Flushing: Clinical Case

…out flushing nor telangiectasias of the face (she reports that she is currently asymptomatic) Vitals: slight tachycardia, otherwise normal No thyromegaly or abdominal masses noted History and exam is concerning for carcinoid tumor syndrome Urine (24…

Therapeutic Strategies in Dermatology

Melanoma: Principles of Management of Melanoma

…ary melanoma (depth of invasion and/or the degree to which the tumor has invaded the skin, as well as ulceration and mitotic index). The major independent risk factor is tumor thickness measured in millimeters (Breslow depth). Depth of invasion is al…

Therapeutic Strategies in Dermatology

Melanoma: Treatment

…commended. Recommended excision margins vary; no international standards yet exist (see Table 3). Table 3. Tumor thickness Recommended excision margins: United States Recommended excision margins: European (Leiter U, et al. 2010) Melanoma in si…

A Clinical Atlas of 101 Common Skin Diseases

Melanoma

…melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly shades of brown. A patch may become a plaque or upon it may develop a papule, nodule, or tumor. A papule may develop into a nod…

Differential Diagnosis in Dermatopathology

Apocrine mixed tumor vs. Eccrine mixed tumor

…melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly shades of brown. A patch may become a plaque or upon it may develop a papule, nodule, or tumor. A papule may develop into a nod…

Therapeutic Strategies in Dermatology

Impetigo: Key Points

Key Points Impetigo is a highly contagious superficial cutaneous infection by Staphylococcus aureus and/or Streptococcus pyogenes. Effective treatment is directed at both organisms. Secondary impetigo, or impetiginization, may complicate preexistin…

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