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Therapeutic Strategies in Dermatology

Melanoma: Key Points

…ration, regression, and mitotic index), by the location of the tumor, by the presence of regional or distant metastases and by the patient characteristics (age, medical co-morbidities). Increased tumor thickness is associated with significant morbidi…

Therapeutic Strategies in Dermatology

Melanoma: Treatment

…commended. Recommended excision margins vary; no international standards yet exist. Table 3. Recommended excision margins based on tumor thickness Tumor thickness Recommended excision margins: United States Recommended excision margins: European…

Therapeutic Strategies in Dermatology

Vascular Birthmarks: Key Points

…benign vascular birthmarks that present in infancy with a wide spectrum of clinical presentations. Recent changes in the classification now restrict the term hemangioma to describe hemangioma of infancy, a benign, self-involuting, endothelial tumor t…

Therapeutic Strategies in Dermatology

Psoriasis: Principles of Psoriasis Management

…lopment of a new class of drugs, engineered proteins targeting specific immunologic mediators involved in psoriasis, including tumor necrosis factor alpha (TNF-A), may offer effective treatments with fewer side effects than the more broadly acting im…

Therapeutic Strategies in Dermatology

Flushing: Clinical Case

…out flushing nor telangiectasias of the face (she reports that she is currently asymptomatic) Vitals: slight tachycardia, otherwise normal No thyromegaly or abdominal masses noted History and exam is concerning for carcinoid tumor syndrome Urine (24…

A Clinical Atlas of 101 Common Skin Diseases

Melanoma

…melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly shades of brown. A patch may become a plaque or upon it may develop a papule, nodule, or tumor. A papule may develop into a nod…

Differential Diagnosis in Dermatopathology

Apocrine mixed tumor vs. Eccrine mixed tumor

…melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly shades of brown. A patch may become a plaque or upon it may develop a papule, nodule, or tumor. A papule may develop into a nod…

Therapeutic Strategies in Dermatology

Psoriasis: References

References Carter JD, Ladhani A, Ricca LR, et al. (2009) A safety assessment of tumor necrosis factor antagonists during pregnancy: a review of the Food and Drug Administration database. J Rheumatol, 36(3):635-41. Griffiths CE, Strober BE, van de Ke…

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