Search Results for: darier's sign

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A Clinical Atlas of 101 Common Skin Diseases

Darier’s Disease

A genetically determined disorder in which numerous closely set keratotic papules are present on the skin, especially the trunk, in nail units, and on mucous membranes, particularly the palate, but also rarely in other parts of the gastrointestinal…

Therapeutic Strategies in Dermatology

Darier’s Disease

A genetically determined disorder in which numerous closely set keratotic papules are present on the skin, especially the trunk, in nail units, and on mucous membranes, particularly the palate, but also rarely in other parts of the gastrointestinal…

Therapeutic Strategies in Dermatology

Darier’s Disease: Treatment

…he starting dose is 0.2-0.3 mg/kg/day, with gradual escalation of the dose to the therapeutic range of 0.5-1 mg/kg/day. Successful use of alitretinoin in Dariers disease has recently been reported. Topical tretinoin 0.025% gel or 0.1% cream before…

Therapeutic Strategies in Dermatology

Darier’s Disease: Key Points

…ant inheritance causing abnormalities of keratinization stemming from defects in calcium regulation in keratinocytes. The classic skin manifestation is an eruption of hyperkeratotic papules, typically in a seborrheic distribution. Characteristic…

Therapeutic Strategies in Dermatology

Darier’s Disease: References

References Abe M, Inoue C, Yokoyama Y, Ishikawa O. (2011). Successful treatment of Dariers disease with adapalene gel, Ped Derm, 28:197-198. Frezzini C, Cedro M, Leao JC, Porter S. (2006). Darier disease affecting the gingival and oral mucosal…

Therapeutic Strategies in Dermatology

Dermatomyositis: Key Points

…h also frequently affects the muscles. Dermatomyositis can be a sign of internal malignancy, with 20% of patients having an associated cancer (ovarian cancer risk, in particular, is elevated). Patients require thorough evaluation for extracutaneous

Therapeutic Strategies in Dermatology

Darier’s Disease: Clinical Case

s on the neck, upper chest Strong family history of Dariers disease Review of systems is notable only for recent fevers in association with worsening rash Presents for management of increasing erythema, crusting on the retroauricular neck, trunk,…

Therapeutic Strategies in Dermatology

Urticaria Pigmentosa / Mastocytosis: Key Points

…occur at any age, and may involve the skin, or affect internal organs including the bone marrow and liver/spleen/lymphatic tissues Urticaria pigmentosa is a form of cutaneous mastocytosis most common in childhood, characterized by brown papules,…

A Clinical Atlas of 101 Common Skin Diseases

Epidermal Nevi

Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines.

Therapeutic Strategies in Dermatology

Candidiasis: Key Points

…ogenital mucosal sites. Predisposing factors include obesity, diabetes, antibiotic or corticosteroid treatments, immunosuppression, removable prostheses, and chronic or frequent exposure to moisture including saliva, fecal and urinary incontinence….

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