A Clinical Atlas of 101 Common Skin Diseases

Sebaceous Gland Hyperplasia

…t of normal pre-existing sebaceous lobules on the face, the forehead, cheeks, and nose in particular, that results in lesions seen clinically to consist of a rim of yellow papules around a central dell that represents a dilated ostium of a follicle….

A Clinical Atlas of 101 Common Skin Diseases

Granuloma Annulare

An inflammatory, i.e., granulomatous, process that usually takes the form of papules which in constellation often assume annular, arcuate, and serpiginous shapes. Many variants exist, among them widespread papules, papules in photodistribution, papu…

A Clinical Atlas of 101 Common Skin Diseases

Dermatofibroma

…ytes, granulomatous inflammation, and fibrosis. As is the case for other fibrosing dermatitides, such as scars and keloids, papules and nodules of dermatofibroma shrink in time and resolve as hyperpigmented macules, some of which even may be delled….

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Fibrosing Dermatitis

…in a longstanding dermatofibroma may be so retracting that a dell comes into being (Fig. 5.375 A&B). Figure 5.365 A&B. The sequence chronological of granulation tissue: replacement invariably by fibroplasia. Granulation tissue, the quinte…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…rtue of the effects of fibrosis, the result being a prominent dell. In short, the scarring process has induced a “dimple,” a sign said to be characteristic of dermatofibroma. 10.20.7A: Nodular dermatitis, fibrohistiocytic + 10.2…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermatofibroma

…inned strikingly; surface of lesion sometimes punctuated by a dell or a hollow Slight acanthosis with hyperpigmentation, often at the periphery of the dermal component No residuum of folliculosebaceous units induced from the epidermis Correlation cl…

Differential Diagnosis in Dermatopathology

Sebaceous hyperplasia vs. Nevus sebaceus of Jadassohn

…ytes, granulomatous inflammation, and fibrosis. As is the case for other fibrosing dermatitides, such as scars and keloids, papules and nodules of dermatofibroma shrink in time and resolve as hyperpigmented macules, some of which even may be delled….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Normal, Typical, Ordinary, Banal, and Common Nevus?

…s of morpho-chromatic features.” Burroni M, Rubegni P, Dell’eva G, et al. The ‘common mole’ from the point of view of digital dermoscopy analysis: subjective vs. objective evaluation of easy pigmented skin lesions. J Eur Acad…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dermatofibroma?

…periphery. Sometimes the lesion in its terminal stage forms a dell. In short, every dermatofibroma eventually shows signs of involution. Histopathologically, the cells in dermatofibroma are inflammatory ones, to wit, histiocytes (macrophages); none i…