Search Results for: dermal dendritic cells

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A Clinical Atlas of 101 Common Skin Diseases

Epidermal Nevi

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Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines.

A Clinical Atlas of 101 Common Skin Diseases

Dermatofibrosarcoma Protuberans

A malignant nonepithelial neoplasm (a sarcoma) presumably of perineural fibrocytes that presents itself usually on the trunk, but sometimes elsewhere, such as the extremities, face, and scalp. A papule of it tends to become a plaque, a nodule, a tum…

Therapeutic Strategies in Dermatology

Bullous Pemphigoid: Key Points

…pathogenesis of BP is due to IgG autoantibodies binding to epidermal antigenic targets and activating inflammatory cascades, including fixing complement, which attracts inflammatory cells and the resultant inflammatory response leads to the character…

Therapeutic Strategies in Dermatology

Lupus: Treatment

…mg/cc) can be administered to active lesions or deeper (i.e., dermal or subcutaneous) lesions. Do not perform this therapy more often than once every 3-4 weeks to minimize atrophy. All patients with CLE should practice strict photoprotection and sun…

Therapeutic Strategies in Dermatology

Lymphomatoid Papulosis: Overview

…yP) is an inflammatory disorder affecting primarily the upper dermal blood vessels. It is characterized by the presence of CD30-positive lymphocytes (sometimes large and atypical) in the dermal infiltrate. Individual lesions resolve spontaneously (al…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…ells, lymphocytes in particular. The term “inflammatory cells” is understood as being generic for neutrophils, eosinophils, lymphocytes, plasma cells, and histiocytes; whether mast cells, basophils, Langerhans” cells, dermal dendroc…

Dermatology Practical & Conceptual

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

…correct diagnosis of their acantholytic dermatosis. Hence, epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection. Indeed, epithelial multinucleated giant cells in the epidermis can be observed not only…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Key Points

…ty. It is believed to be mediated by IgA autoantibodies to epidermal transglutaminase. Dapsone is the first-line therapy for DH. Strict gluten avoidance is essential. Though gluten avoidance ultimately may prevent recurrence of DH flares, avoidance o…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dermal Papilla?

…20;Historically, the hair germ has been defined as a group of cells located at the base of the telogen follicle in close contact with the dermal papilla.” Lavker RM, Miller S, Wilson C, et al. Hair follicle stem cells: their location, role in h…

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