Search Results for: dermoepithelial interface

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Therapeutic Strategies in Dermatology

Lupus: Key Points

…confirmed by skin biopsy, which in general reveals a vacuolar interface dermatitis, often in association with a lymphocytic infiltrate with plasma cells, epidermal atrophy, and mucin. Variants exist, such as bullous lupus, which is marked by the pres…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermoepithelial Interface

…e skin of patients with Marfan’s syndrome. Although the dermoepithelial interface is known now to be composed of many elements, few of which were recognized 27 years ago when the first edition of this book was published, many more doubtless wil…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Key Points

…pathic pernio may undergo skin biopsy, and should features of interface dermatitis and histologic findings suggestive of lupus be noted, those patients should undergo an evaluation for possible chilblain lupus erythematosus. The presence of angulated…

Therapeutic Strategies in Dermatology

Melanoma: Key Points

…is only without involvement of the papillary-reticular dermal interface III Invasion to the papillary dermis without extension into the reticular dermis IV Invasion into the reticular dermis without involvement of subcutaneous tissue V Invasion into…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…lymphocytes, and vacuolar alteration along the dermoepidermal interface, and a perivascular and interstitial infiltrate of lymphocytes = Erythema multiforme + Individual necrotic keratocytes, lymphocytes, neutrophils, and eosinophils in conjunction w…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.63.1A: Perivascular dermatitis, interface, vacuolar + 10.63.1B: Smudged appearance of the dermoepidermal junction, focally thinned epidermis, and plentiful mucin throughout the dermis = Lupus erythematosus, discoid  The presence of paraker…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.66.1A: Perivascular dermatitis, interface, vacuolar + 10.66.1B: Lymphocytes along the dermoepidermal junction and in the spinous zone, and ballooned and necrotic keratocytes = Mucha-Habermann disease, acute That this lesion is recent in on…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…oted to “confusing terms” later in this chapter.) DERMOEPITHELIAL INTERFACE [Gk. dermis (skin) + epithelial (pertaining to an epithelium) + NE. interface (boundary between two things)]: The junction between dermis and epithelial structure…

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