Therapeutic Strategies in Dermatology

Epidermolysis Bullosa: Overview

Overview Epidermolysis bullosa (EB) is a heterogeneous group of inherited mechanobullous diseases. Three basic forms are recognized, based on the electron microscopic level of the blister formation. The ideal strategy would be to correct the genetic…

Histologic Diagnosis of Inflammatory Skin Diseases

Epidermolysis bullosa simplex

Epidermolysis bullosa simplex Presentation stereotypical Age and sex Shortly after birth or during childhood and adolescence; both sexes affected Distribution of lesions Varies according to type of epidermolysis bullosa (see Variations clinical) Ind…

Histologic Diagnosis of Inflammatory Skin Diseases

Polymorphous light eruption

Polymorphous light eruption Synonyms Polymorphic light eruption Summer prurigo Summer eruption Eczema solare Prurigo aestivalis Chronic polymorphous light eruption Hutchinson’s summer prurigo Presentation stereotypical Age and sex Young wome…

Histologic Diagnosis of Inflammatory Skin Diseases

Darier’s disease and simulators of it

Darier’s disease and simulators of it Synonyms Darier-White disease Presentation stereotypical Age and sex Onset in childhood or adolescence in both sexes Distribution of lesions Symmetrical and widespread, favoring the neck, shoulders, upper…

Histologic Diagnosis of Inflammatory Skin Diseases

Suggested Readings

Inflammation Belizova Z. Inflammatory disease? Dermatopathol: Prac & Concep 2004;10(2):8, available at www.derm101.com B?er A, Phadke V, Ackerman AB. Inflammatory disease—In search of a definition of a term employed commonly. Dermatopathol: Prac…