Search Results for: drug eruptions

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A Clinical Atlas of 101 Common Skin Diseases

Drug Eruptions

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An inflammatory process that results from the effects of a drug administered systemically, e.g., by ingestion, inhalation, injection, or application rectally, and manifested usually by lesions distributed widely and symmetrically.

A Clinical Atlas of 101 Common Skin Diseases

Fixed Drug Eruption

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Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the genitalia, perioral region, and hands, in response to systemic administration of a particular drug or chemical, chief among them barbiturates and sulfonamides.

A Clinical Atlas of 101 Common Skin Diseases

Drug Eruptions

An inflammatory process that results from the effects of a drug administered systemically, e.g., by ingestion, inhalation, injection, or application rectally, and manifested usually by lesions distributed widely and symmetrically. Any of the many…

Therapeutic Strategies in Dermatology

Drug Eruptions

An inflammatory process that results from the effects of a drug administered systemically, e.g., by ingestion, inhalation, injection, or application rectally, and manifested usually by lesions distributed widely and symmetrically. Any of the many…

A Clinical Atlas of 101 Common Skin Diseases

Fixed Drug Eruption

…ef among them barbiturates and sulfonamides. It is the only type of drug eruption that can be diagnosed with surety histopathologically, the findings in it being entirely specific, unlike the situation in drug eruptions of all other kinds….

Therapeutic Strategies in Dermatology

Drug Eruptions: Key Points

…rythema Multiforme.) Most adverse cutaneous reactions to medications represent a benign side effect; however, in rare cases, drug eruptions may have associated systemic complications with significant morbidity and/or mortality. There are four key…

Therapeutic Strategies in Dermatology

Drug Eruptions: Therapy

…oids should be used judiciously, as corticosteroids have been associated with increased morbidity when used in some systemic drug eruptions such as TEN. If the patient has systemic involvement concerning for drug hypersensitivity reaction,…

Therapeutic Strategies in Dermatology

Photosensitivity Dermatoses: Overview

…e tissue disorders, and pellagrous dermatitis must be ruled out in all patients who develop a chronic course. Photosensitive Drug Eruptions Photosensitive drug eruptions may present either as sunburn (a phototoxic response) or photoallergy (an…

Therapeutic Strategies in Dermatology

Drug Eruptions: Initial Evaluation

Initial Evaluation Differential diagnosis Drug hypersensitivity, i.e., DRESS (drug reaction with eosinophilia and systemic symptoms): Marked facial edema in association with a morbilliform eruption is concerning for DRESS. Viral exanthem: A viral…

Therapeutic Strategies in Dermatology

Linear IgA Dermatosis: Overview

…nd glibenclamide. The therapeutic strategy is relief of symptoms and control of blister formation. Treatment First Steps For drug induced disease, discontinue the culprit drug. For idiopathic disease, treat with dapsone as described below: a. Linear…

Therapeutic Strategies in Dermatology

Balanitis: Overview

…ronidazole 500 mg twice daily for 5 days. Evaluate the patient for diabetes mellitus. Take a careful history of intermittent drug ingestion to rule out a fixed drug eruption. Evaluate the sexual partner(s) for infection with C. albicans, T….

Therapeutic Strategies in Dermatology

Erythema Multiforme: Treatment

…revent progression of ocular disease. Note: Sulfa-containing eye drops should be avoided if there is any concern for a sulfa drug related EM or SJS. When to refer to a dermatologist When the diagnosis of erythema multiforme is not clear. If EM is…

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