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A Clinical Atlas of 101 Common Skin Diseases

Drug Eruptions

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An inflammatory process that results from the effects of a drug administered systemically, e.g., by ingestion, inhalation, injection, or application rectally, and manifested usually by lesions distributed widely and symmetrically.

A Clinical Atlas of 101 Common Skin Diseases

Fixed Drug Eruption

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Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the genitalia, perioral region, and hands, in response to systemic administration of a particular drug or chemical, chief among them barbiturates and sulfonamides.

A Clinical Atlas of 101 Common Skin Diseases

Drug Eruptions

An inflammatory process that results from the effects of a drug administered systemically, e.g., by ingestion, inhalation, injection, or application rectally, and manifested usually by lesions distributed widely and symmetrically. Any of the many ex…

Therapeutic Strategies in Dermatology

Drug Eruptions

An inflammatory process that results from the effects of a drug administered systemically, e.g., by ingestion, inhalation, injection, or application rectally, and manifested usually by lesions distributed widely and symmetrically. Any of the many ex…

A Clinical Atlas of 101 Common Skin Diseases

Fixed Drug Eruption

Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the genital…

Therapeutic Strategies in Dermatology

Drug Eruptions: Initial Evaluation

…ion Adverse reactions to medications are common, and cutaneous drug eruptions may occur in 3% of all hospitalized patients who are receiving medications. They can represent 1% of consultations in office-based dermatology practices. Drug eruptions may…

Therapeutic Strategies in Dermatology

Drug Eruptions: Therapy

…ients require systemic corticosteroids for management of their drug reaction. Note that systemic steroids should be used judiciously, as corticosteroids have been associated with increased morbidity when used in some systemic drug eruptions such as T…

Therapeutic Strategies in Dermatology

Photosensitivity Dermatoses: Overview

…t in all patients who develop a chronic course. Photosensitive Drug Eruptions Photosensitive drug eruptions may present either as sunburn (a phototoxic response) or photoallergy (an eczematous response). Photoallergic eruptions may be either eczemato…

Therapeutic Strategies in Dermatology

Drug Eruptions: Key Points

…ations represent a benign side effect; however, in rare cases, drug eruptions may have associated systemic complications with significant morbidity and/or mortality. There are four key steps to the evaluation of a drug rash: Is it a drug eruption? I…

Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides: Overview

…neous lesions in an effort to maintain a high quality of life. Drug eruptions, chronic actinic dermatitis, and, rarely, allergic contact dermatitis can have histologic features very similar to CTCL. Even T-cell gene rearrangement studies may be posit…

Therapeutic Strategies in Dermatology

Balanitis: Overview

…ows therapy in the office to ensure compliance. Take a careful drug history to rule out a fixed drug eruption. Consider the possibility of an allergic contact dermatitis (e.g., from condoms or vaginal hygiene spray). Biopsy patients not responding to…

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