Search Results for: dyskeratosis

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Therapeutic Strategies in Dermatology

Darier’s Disease: References

…IJD, 44:184-192. Savignac M, Edir A, Simon M, Hovnanian A. (2011). Darier disease: a disease model of impaired calcium homeostasis in the skin, Biochimica et Biophysica Acta, 1813:1111-1117. Zeglaoui F, Zaraa I, Fazaa B, et al. (2005). Dyskeratosis

Therapeutic Strategies in Dermatology

Darier’s Disease: Key Points

…ticulum; the resulting disruption in calcium homeostasis in keratinocytes results in poor cell-cell adhesion with subsequent dyskeratosis affecting skin, nails, and mucous membranes. The hallmark skin lesion is a hyperkeratotic papule. The diagnosis…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Clinical Case

…ure from crusted area Follow-up evaluation H&E demonstrates intraepidermal and suprabasal acantholysis without prominent dyskeratosis Bacterial culture was negative Initiate treatment with: aluminum chloride 20% solution, clindamycin 1%,…

Therapeutic Strategies in Dermatology

Grover’s Disease / Transient Acantholytic Dermatosis: References

…te G, Cornelius L (2012). Unusual complication of vemurafenib treatment of metastatic melanoma: exacerbation of acantholytic dyskeratosis complicated by Kaposi varicelliform eruption, JAAD, 148:966-968. Norman R and Chau V (2011). Use of etanercept…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Key Points

…s extending down to the suprabasal level, producing the characteristic “dilapidated brick wall” appearance in the epidermis. Dyskeratosis is not a prominent feature, in contrast to the findings seen in Darier’s disease. As HHD is not an…

Dermoscopic clues to diagnose acantholytic dyskeratosis

Dermoscopic clues to diagnose acantholytic dyskeratosis

…One theory is that the accumulation in the skin of chemotherapy metabolites by sweating may be related to the development of dyskeratosis and acantholysis; another theory supposes that acantholytic dyskeratosis may represent an off-target effect of…

Acantholytic dyskeratotic acanthoma: case report and review of the literature

Acantholytic dyskeratotic acanthoma: case report and review of the literature

…the time of biopsy and healed without evidence of recurrence at the subsequent visit. Conclusion The term focal acantholytic dyskeratosis was originally used to describe incidental lesions with acantholysis and dyskeratosis; however, when these…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…that reason, Darier’s disease rarely is associated with corneocytes in basket-weave pattern above foci of acantholytic dyskeratosis. A tad of parakeratosis is seen in the focus of acantholytic dyskeratosis shown at high magnification….

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