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Therapeutic Strategies in Dermatology

Herpes Simplex: Treatment

…uperinfection (usually S. aureus) and treat appropriately. For eczema herpeticum, treat the underlying atopic dermatitis as well. For genital HSV, evaluate for other sexually transmitted infections. For the immunosuppressed, topical acyclovir 5% oint…

Therapeutic Strategies in Dermatology

Hand Dermatitis: References

References Coenraads PJ (2012) Hand eczema, NEJM, 367: 1829-1837. Bissonnette R et al (2010) Redefining treatment options for chronic hand eczema, JEADV, 24 (Suppl.3): 1-20. Dirschka T et al (2008) An open-label study assessing the safety and effica…

Therapeutic Strategies in Dermatology

Nummular Dermatitis: Overview

Overview Eczema is an all-inclusive term for dermatitis of diverse origin, including atopic dermatitis, dyshidrotic eczema, hand eczema, seborrheic dermatitis, and stasis dermatitis (see appropriate chapters for descriptions of therapy for these dis…

Therapeutic Strategies in Dermatology

Herpes Simplex: Initial Evaluation

…tlow may occur when digits are exposed to herpetic lesions. Eczema herpeticum, superinfection of atopic dermatitis with HSV, is common and can be difficult to distinguish from impetiginized eczema (i.e., atopic dermatitis with bacterial superinfec…

Therapeutic Strategies in Dermatology

Herpes Simplex: Key Points

…a pre-existing skin disease (usually atopic dermatitis, e.g., eczema herpeticum). Acyclovir is almost always the first-line treatment given to individuals with healthy immune systems; in immunosuppressed individuals (especially HIV-infected persons)…

Therapeutic Strategies in Dermatology

Impetigo: Initial evaluation

…s with scalloped borders are suggestive of herpes. Eczema herpeticum: Superinfection of atopic dermatitis with herpes or impetiginizing bacteria (staphylococcus or streptococcus) is common and can be difficult to distinguish clinically. B…

Therapeutic Strategies in Dermatology

Atopic Dermatitis: Principles of Management of Atopic Dermatitis

Principles of Management of Atopic Dermatitis Effective management must address 4 major issues: Skin barrier: Repairing the barrier through hydration and emollients Inflammation: Use of an anti-inflammatory agent, either topical or systemic In mos…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Initial Evaluation

Initial Evaluation Herpes zoster (shingles) Note that vesicles and papulovesicular lesions are grouped with an erythematous to hemorrhagic base. Primary varicella infection Differential diagnosis Herpes simplex virus (oral…

Therapeutic Strategies in Dermatology

Atopic Dermatitis: References

References Williams HC, Grindlay DJ. What’s new in atopic eczema? An analysis of systematic reviews published in 2007 and 2008. Part 1. Definitions, causes and consequences of eczema. Clin Exp Dermatol. 2010;35(1):12-15. Darsow U, Wollenberg A, Simo…

Therapeutic Strategies in Dermatology

Photosensitivity Dermatoses: Overview

…either as sunburn (a phototoxic response) or photoallergy (an eczematous response). Photoallergic eruptions may be either eczematous or lichenoid histologically. It may be impossible to clearly define the pattern of eruption clinically. The most imp…

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