Search Results for: elastophagocytosis

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Actinic Granuloma?

…nular elastolytic giant cell granuloma (AEGCG) are terms commonly applied to cutaneous lesions characterized by elastolysis, elastophagocytosis and a multinucleated cell infiltrate…The tissue changes of AG and AEGCG are identical and differ…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ermis are not specific for Crohn’s disease. Neither is the presence of elastotic material in histiocytes, i.e., “elastophagocytosis”; it can be observed in any granulomatous process that occurs in skin damaged badly by sunlight,…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…nd a perivascular lymphoplasmacytic infiltrate = Necrobiosis lipoidica + Histiocytes, some of them at times with evidence of elastophagocytosis, in company with a sparse infiltrate of lymphocytes in interstitial array in foci = Mycosis fungoides,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…nucleate, in company with mucin between collagen bundles = Granuloma annulare The presence of elastic fibers in histiocytes (elastophagocytosis), as shown here, is not a finding that has import diagnostic in itself. When it occurs in histiocytes of…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…ma annulare. Reason: The features of it clinical and the findings of it histopathologic are those of granuloma annulare, the elastophagocytosis claimed to be characteristic of it being expected in any granulomatous process that occurs on skin…

Actinic granuloma

Actinic granuloma

…c granuloma is multinucleated foreign body giant cells, which phagocytize the degenerated elastic fibers, a process known as elastophagocytosis. There is an absence of necrobiosis, such as facial necrobiosis lipoidica, or mucinosis, such as GA or…

Histologic Diagnosis of Inflammatory Skin Diseases

Kimura’s disease

…stiocytoid hemangioma,” represent a pattern histopathologic analogous to those of granular cellularity, flame figures, elastophagocytosis, epidermolytic hyperkeratosis, focal acantholytic dyskeratosis, and epithelial mucinosis, they being the…

Differential Diagnosis in Dermatopathology

Discussions

…e reticular dermis; some multinucleate histiocytes (histiocytic giant cells) are present episodically in the infiltrate; and elastophagocytosis by histiocytes is notable sometimes. When histiocytes are disposed in interstitial array in patches of…