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Histologic Diagnosis of Inflammatory Skin Diseases

Elastosis perforans serpiginosa

Elastosis perforans serpiginosa Synonyms Elastoma intrapapillare perforans verruciforme Keratosis follicularis serpiginosa Serpiginous perforating elastosis Perforating elastoma Elastoma intrapapillare perforans Presentation stereotypical Age and…

A Clinical Atlas of 101 Common Skin Diseases

Porphyria Cutanea Tarda

A disease manifested chiefly in the skin by vesicles and bullae that appear on sites of trauma, especially the face and dorsa of the hands, often in conjunction with macular hyperpigmentation and hypertrichosis of a face and sclerodermoid changes on…

A Clinical Atlas of 101 Common Skin Diseases

Seborrheic Keratosis, Including Solar Lentigo

A benign neoplasm of keratinocytes that consists of pigmented macules, papules, and plaques distributed on sun-exposed sites for a solar lentigo and the reticulated type of seborrheic keratosis, which represents a later stage of solar lentigo, and o…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perforating Diseases?

…ude perforating granuloma annulare, perforating folliculitis, elastosis perforans serpiginosa and reactive perforating collagenosis.” Mehregan A. Perforating dermatoses: a clinicopathologic review. Int J Dermatol 1977;16:1927. “Perforat…

Differential Diagnosis in Dermatopathology

Discussions

Perforating folliculitis and elastosis perforans serpiginosa have several findings histopathologic in common: an epithelial channel through surface epidermis; neutrophils in the channel; a collection of neutrophils contiguous with the channel; foci…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reactive Perforating Collagenosis?

…assified currently as “perforating” ones, namely, elastosis perforans serpiginosa, perforating folliculitis, and reactive perforating collagenosis, are completely unrelated and different from one another; therefore, they should not be gro…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…o enlarge. + Well-preserved dermal papillae and neither solar elastosis nor rim of homogenous eosinophilic material around small vessels in the upper part of the dermis = Suction blister + Erythrocytes in the blister, holes (gas bubbles) in the der…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…10.26.1C + 10.26.1D + 10.26.1E + 10.26.1F = Elastosis perforans serpiginosa induced by penicillamine ┬áIn the upper half of the dermis of conventional elastosis perforans serpiginosa are countless lightly stained but similar elastic…

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