Search Results for: eosinophilia

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Therapeutic Strategies in Dermatology

Drug Eruptions: Initial Evaluation

Initial Evaluation Differential diagnosis Drug hypersensitivity, i.e., DRESS (drug reaction with eosinophilia and systemic symptoms): Marked facial edema in association with a morbilliform eruption is concerning for DRESS. Viral exanthem: A viral…

Therapeutic Strategies in Dermatology

Leprosy/Hansen’s Disease and Reactional States: Overview

…sone may also cause an infectious mononucleosis-like hypersensitivity syndrome, with fever, myalgias, adenopathy, hepatitis, eosinophilia, and rash. Clofazimine regularly causes a red to purple-black coloration of the skin that is accentuated in the…

Therapeutic Strategies in Dermatology

Drug Eruptions: Suggested Reading

…AR-Study. JID 128: 35. Friedmann PS, Pickard C, Ardern-Jones M, Bircher AJ (2010). Drug-induced exanthemata: a source of clinical and intellectual confusion. Eur J Dermatol 20(3): 255-9. Chen Y-C, Chiu H-C, Chu C-Y (2010). Drug reaction with…

Therapeutic Strategies in Dermatology

Drug Eruptions: Therapy

…rugs such as dilantin and allopurinol are possible offenders. Common findings of systemic involvement include: leukocytosis, eosinophilia, thrombocytopenia, renal impairment, transaminitis, and elevated creatine kinase (sign of myositis). A skin…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Treatment

…induced hypersensitivity syndrome with fever, myalgias, adenopathy, hepatitis, morbilliform rash, and often (but not always) eosinophilia. The diagnosis of dermatitis herpetiformis should be reevaluated in patients who do not respond to…

Therapeutic Strategies in Dermatology

Erythema Elevatum Diutinum: Treatment

…nduced hypersensitivity syndrome, with fever, myalgias, adenopathy, hepatitis, morbilliform rash, and often (but not always) eosinophilia. When to refer to a dermatologist When the diagnosis is not clear. If a skin biopsy is necessary to confirm the…

Therapeutic Strategies in Dermatology

Cutaneous Larva Migrans & Larva Currens: Initial Evaluation: Larva Currens

…s of dissemination, larvae may be found in a wide variety of body fluids. Larvae may also be seen in lesional skin biopsies. Eosinophilia is also common, though a nonspecific finding. Differential diagnosis Similar to that of cutaneous larva migrans…

Therapeutic Strategies in Dermatology

Cutaneous Larva Migrans & Larva Currens: Key Points: Larva Currens

…th purpuric lesions on the abdomen (classically in a periumbilical distribution) due to massive larval migration within the skin. This situation may present with severe systemic manifestations and septic shock. Eosinophilia is often but not always…

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