Search Results for: epidermis

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Histologic Diagnosis of Inflammatory Skin Diseases

Epidermis

Generative cells of the epidermis, follicles, and nail units all mature to become dead cornified cells that contain large quantities of the protein, keratin. The filament of cornified cells that takes the form of hair is akin to the layer of cornifi…

Dermatology Practical & Conceptual

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

Abstract Background: Multinucleated giant cells in the epidermis can either be epithelial or histiocytic. Epithelial multinucleated giant cells are most often associated with herpes virus infections. Purpose: To review the histologic differential di…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…calized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcutaneous fat, or in parts of any other organ (Fig. 3.1), and it may come into being by virtue of infection or indep…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…matory Cells Lymphocytes with large pleomorphic nuclei in the epidermis, dermis, or subcutaneous fat or at a combination of those sites; synonymous with “atypical lymphocytes.” Click image to enlarge. + Mouth parts of a tick in the dermis…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…being testimony to spongiosis having been present within the epidermis, the collarettes representing the residuum of a mound of parakeratosis that largely desquamated. A plaque of nummular dermatitis is given to display crusts as well as scales. Nea…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…henoid + 11.14.1B: Lymphocytes, sparse in both the dermis and epidermis, larger in the epidermis than in dermis, solitary in the basal layer in foci, and in association with scant spongiosis in the spinous zone = Mycosis fungoides, patch  The diagnos…

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

…either ectoderm or mesoderm. The epithelial structures, i.e., epidermis (surface and infundibular), apocrine units, sebaceous units, hair follicles, eccrine units, and nail units, come from ectoderm. Melanocytes, nerves, and specialized sensory recep…

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