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A Clinical Atlas of 101 Common Skin Diseases

Necrobiosis Lipoidica

A granulomatous inflammatory process characterized clinically by patches that become yellowish plaques and that in time resolve with atrophy and telangiectases. The condition usually occurs in persons with diabetes….

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Nodular and Diffuse Dermatitis

…s but a lymphoma. Figure 5.175 A&B. A nodule made up of epithelioid histiocytes: sarcoidosis. The nodular infiltrate throughout the dermis and in subcutaneous fat is composed mostly of epithelioid histiocytes, which qualifies this process as g…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…exhibit dense infiltrates of lymphocytes around collections of epithelioid histiocytes, e.g., some lesions of subcutaneous sarcoidosis, and even display necrosis in the center of clusters of epithelioid cells. Sarcoidal granulomas form in response to…

Histologic Diagnosis of Inflammatory Skin Diseases


…odular dermatitis, granulomatous + 10.95.2B: Collection of epithelioid histiocytes, some cells of which are multinucleate, in association with a few lymphocytes = Sarcoidosis  The near absence of lymphocytes from the vicinity of epithelioid tuber…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology


…eprosy may, on occasion, be sarcoidal rather than tuberculoid. Epithelioid-cell nevus is one of many synonyms for Spitz nevus. To date, there has yet to be a comprehensible description of the epithelioid melanocytes said to constitute that distinctiv…

Dermatology Practical & Conceptual

Tufted hemangioma: clinical case and literature review

Abstract Tufted hemangiomas are relatively rare benign vascular proliferations that are congenital or appear during the first years of life. Herein we present an additional case of tufted hemangioma that appeared one year after birth and discuss its…

Histologic Diagnosis of Inflammatory Skin Diseases


Sarcoidosis Synonyms Boeck’s disease Boeck sarcoid Benign lymphogranulomatosis Presentation stereotypical Age and sex Young adults of both sexes Distribution of lesions Face and extremities especially Arrangement of lesions Scattered Configu…

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