Dermatology Practical & Conceptual

From the Dermatologikum Hamburg: Quiz

…Figure 2A-H. What is your diagnosis? Answer and explanation Erythropoietic protoporphyria (EPP), late onset. In this patient, the history of photosensitivity combined with red and painful skin lesions should raise the suspicion of EPP. However, the…

Histologic Diagnosis of Inflammatory Skin Diseases

Porphyria cutanea tarda

…per part of the dermis are a clue to porphyria cutanea tarda, erythropoietic protoporphyria, and, uncommonly, discoid lupus erythematosus. A subepidermal blister above solar elastosis in a dermis practically devoid of an infiltrate of inflammatory ce…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…ay be observed in some lesions of porphyria cutanea tarda and erythropoietic protoporphyria. Abundant mucin in the reticular dermis in conjunction with perivascular infiltrates of lymphocytes is a clue to lupus erythematosus, but also to dermatomyosi…

Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

…flammatory disease. Other expressions of porphyria, e.g., the erythropoietic, and of epidermolysis bullosa, e.g., the acquired, are affiliated consistently with infiltrates of inflammatory cells, few in the former and many in the latter. For that rea…