Dermatology Practical & Conceptual

From the Dermatologikum Hamburg: Quiz

…injury in myeloproliferative disorder secondary to late-onset protoporphyria caused by deletion of a ferrochelatase gene in hematopoietic cells. Blood. 2006;107(1):60-2. 3. Todd DJ. Erythropoietic protoporphyria. Br J Dermatol. 1994;131(6):751-6….

Histologic Diagnosis of Inflammatory Skin Diseases

Porphyria cutanea tarda

…pper part of the dermis are a clue to porphyria cutanea tarda, erythropoietic protoporphyria, and, uncommonly, discoid lupus erythematosus. A subepidermal blister above solar elastosis in a dermis practically devoid of an infiltrate of inflammatory c…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…may be observed in some lesions of porphyria cutanea tarda and erythropoietic protoporphyria. Abundant mucin in the reticular dermis in conjunction with perivascular infiltrates of lymphocytes is a clue to lupus erythematosus, but also to dermatomyos…

Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

The algorithmic method proposed in these pages and predicated on patterns histopathologic is intended to be more than just a guide to diagnosis of particular pathologic processes in skin and subcutaneous fat; it is meant to serve as a springboard fo…