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A Clinical Atlas of 101 Common Skin Diseases

Melanocytic Nevi and Melanotic Macules

…melanocytic nevi) of various specific types, all of which are composed of abnormal melanocytes and manifested clinically as lesions of different colors, shapes, and sizes, among them, macules and patches, papules and plaques, and nodules and tumors….

A Clinical Atlas of 101 Common Skin Diseases

Melanoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

A Clinical Atlas of 101 Common Skin Diseases

Vitiligo

An inflammatory process that is idiopathic and results in depigmentation of the skin consequent to loss of melanocytes from the epidermis, and in whitening of hair that follows loss of melanocytes from the bulb of follicles….

A Clinical Atlas of 101 Common Skin Diseases

Melasma

…macules and patches mostly in the middle third of the face, vertically and horizontally, distributed symmetrically and occurring mainly in postpubescent women as a consequence of the combined effects of estrogen and ultraviolet light on melanocytes….

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Overview

Overview Hailey-Hailey disease (HHD), also called benign familial pemphigus, is an autosomal-dominant disorder characterized by a defect in keratinocyte adhesion. HHD most frequently involves intertriginous areas, where exacerbations are triggered b…

Therapeutic Strategies in Dermatology

Porokeratosis: Overview

…gnant. Any papule, nodule, or ulcer developing in association with a lesion of porokeratosis must be biopsied. Porokeratosis is an autosomally dominantly inherited genetic trait. Genetic counseling is appropriate in familial cases. Topical 5-FU thera…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Key Points

…condition that occurs in cold, damp environments and presents with symmetric, distal, transient red-to-purple lesions on the extremities. Treatment is centered on keeping the patient warm and avoiding exposure to cold, damp environments. Cases which…

Therapeutic Strategies in Dermatology

Facial Melanosis, Melasma: Key Points

…igment in the epidermis, dermis, or both; increased number of melanocytes or dermal melanophages in the dermis may also result in melasma. It usually appears in association with estrogen exposure in the form of oral contraceptive (OCP) use, hormone r…

Therapeutic Strategies in Dermatology

Melanoma: Key Points

…cted patients. Introduction Melanoma is a malignant tumor of melanocytes residing in skin, mucosal sites, eye, and meninges. In the United States, the incidence is 10-25 per 100,000 persons, with approximately 76,100 new cases of melanoma and 9,710…

Therapeutic Strategies in Dermatology

Urticaria Pigmentosa / Mastocytosis: References

…lin Dermatol 12, 259-270. Fett NM, Teng J, Longley BJ (2013). Familial urticarial pigmentosa: report of a family and review of the role of KIT mutations. Am J Dermatopathol, 35, 113-116 Frieri M, Quershi M (2013). Pediatric mastocytosis: a review of…

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