Search Results for: familial melanopathy with gigantic melanocytes

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A Clinical Atlas of 101 Common Skin Diseases

Melanocytic Nevi and Melanotic Macules

…benign neoplasms (“acquired” melanocytic nevi) of various specific types, all of which are composed of abnormal melanocytes and manifested clinically as lesions of different colors, shapes, and sizes, among them, macules and patches,…

A Clinical Atlas of 101 Common Skin Diseases

Melanoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate,…

A Clinical Atlas of 101 Common Skin Diseases

Vitiligo

An inflammatory process that is idiopathic and results in depigmentation of the skin consequent to loss of melanocytes from the epidermis, and in whitening of hair that follows loss of melanocytes from the bulb of follicles.

A Clinical Atlas of 101 Common Skin Diseases

Melasma

…ird of the face, vertically and horizontally, distributed symmetrically and occurring mainly in postpubescent women as a consequence of the combined effects of estrogen and ultraviolet light on melanocytes….

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Key Points

Key Points Chilblains (pernio) is a benign condition that occurs in cold, damp environments and presents with symmetric, distal, transient red-to-purple lesions on the extremities. Treatment is centered on keeping the patient warm and avoiding…

Therapeutic Strategies in Dermatology

Porokeratosis: Overview

…s must be biopsied. Porokeratosis is an autosomally dominantly inherited genetic trait. Genetic counseling is appropriate in familial cases. Topical 5-FU therapy can cause severe skin inflammation. Patients must be counseled carefully and followed…

Therapeutic Strategies in Dermatology

Facial Melanosis, Melasma: Key Points

…er cutaneous lip. It results from increased epidermal melanin pigment in the epidermis, dermis, or both; increased number of melanocytes or dermal melanophages in the dermis may also result in melasma. It usually appears in association with estrogen…

Therapeutic Strategies in Dermatology

Melanoma: Key Points

…e management of metastatic melanoma and extend survival for affected patients. Introduction Melanoma is a malignant tumor of melanocytes residing in skin, mucosal sites, eye, and meninges. In the United States, the incidence is 10-25 per 100,000…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Key Points

…ic antibiotics as well as systemic immunomodulators may be employed. Introduction Hailey-Hailey disease (HHD), also known as familial benign chronic pemphigus, is a rare autosomal dominantly inherited genodermatosis with complete penetrance in…

Therapeutic Strategies in Dermatology

Urticaria Pigmentosa / Mastocytosis: Key Points

…curs in patients of all ethnic backgrounds and in both men and women. Most cases are sporadic, but there are rare cohorts of familial cases, including disease reported in monozygotic twins. Cases of adult mastocytosis have been identified with…

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