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Therapeutic Strategies in Dermatology

Eosinophilic Fasciitis: Overview

…ory and markedly symptomatic patients. Pitfalls Eosinophilic fasciitis must be distinguished from scleroderma. Recognition is critical because therapy and prognosis are radically different. Refractory cases of eosinophilic fasciitis may represent m…

Therapeutic Strategies in Dermatology

Drug Eruptions: Therapy

…, it is reasonable to attempt a re-challenge of the medication with close monitoring. In some cases, adverse drug reactions do not occur upon repeat exposure. Patients with a history of severe cutaneous eruption, especially with systemic complication…

Therapeutic Strategies in Dermatology

Drug Eruptions: Suggested Reading

Suggested Reading Mockenhaupt M et al (2008). Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-Study. JID 128: 35. Friedmann PS, Pickard C, Ardern-Jones M,…

Therapeutic Strategies in Dermatology

Leprosy/Hansen’s Disease and Reactional States: Overview

…se an infectious mononucleosis-like hypersensitivity syndrome, with fever, myalgias, adenopathy, hepatitis, eosinophilia, and rash. Clofazimine regularly causes a red to purple-black coloration of the skin that is accentuated in the lesions. This is…

Therapeutic Strategies in Dermatology

Drug Eruptions: Initial Evaluation

…al diagnosis Drug hypersensitivity, i.e., DRESS (drug reaction with eosinophilia and systemic symptoms): Marked facial edema in association with a morbilliform eruption is concerning for DRESS. Viral exanthem: A viral exanthem may be clinically indis…

Therapeutic Strategies in Dermatology

Erysipelas/Cellulitis: Treatment

…lulitis in patients who are high risk for recurrence. Patients with systemic symptoms, significant neutrophilia, diabetes mellitus, immunosuppression, neutropenia, erysipelas of the face, associated with decubitus ulcers, or cellulitis on dependent e…

Therapeutic Strategies in Dermatology

Erysipelas/Cellulitis: Key Points

…More serious soft tissue infections, such as early necrotizing fasciitis, may resemble cellulitis. Erysipelas is a superficial form of cellulitis that involves superficial lymphatics located within the upper dermis. Beta-hemolytic streptococci are th…

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