Search Results for: fibrin

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A Clinical Atlas of 101 Common Skin Diseases

Allergic (Leukocytoclastic) Vasculitis

A systemic inflammatory process involving venules by deposits of fibrin within their wall in conjunction with neutrophils and nuclear “dust” of neutrophils in the dermis and, at times, the subcutaneous fat. The clinical manifestations…

A Clinical Atlas of 101 Common Skin Diseases

Livedo Vasculitis and Livedo Reticularis

A type of small-vessel vasculitis (venulitis) of the skin, occurring especially in the vicinity of the ankle, characterized at first by purpuric macules and patches that, in time, may become hemorrhagic blisters that ulcerate and heal with white,…

Therapeutic Strategies in Dermatology

Livedo / Livedoid Vasculopathy / Atrophie Blanche: Initial Evaluation

…thin small vessels in the mid and upper dermis and endothelial cell proliferation. A perivascular lymphocytic infiltrate and fibrinoid material in the vessel wall may be seen but true vasculitis is rare (and is thought to result from the primary…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…sculitis, small-vessel, neutrophilic + 10.58.8B: Neutrophils and nuclear “dust” of neutrophils in the dermis and fibrin in the wall of venules, reticular alteration, and necrosis of keratocytes = Leukocytoclastic vasculitis, fully…

Histologic Diagnosis of Inflammatory Skin Diseases

Rheumatoid nodule

…icular dermis and/or the subcutaneous fat Neutrophils and nuclear “dust” of neutrophils scattered in the mass of fibrin Fibrin surrounded by thin histiocytes aligned in a palisade Fibrosis, sometimes extensive, in the region beyond the…

Histologic Diagnosis of Inflammatory Skin Diseases

Livedo vasculitis

…oclastic vasculitis is attended by abundant nuclear “dust” of neutrophils. Septic vasculitis is unaccompanied by fibrin in the wall of venules. Clue to specific diagnosis histopathologic Fibrin in the wall of venules and thrombi in the…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…ranuloma” Histiocytes, usually epithelioid ones, in radial array around a focus marked by degenerated collagen, mucin, fibrin, or a foreign body, etc., and more accurately described as histiocytes arranged in a palisade. Click image to…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Vasculitis?

…that is, nuclear “dust” of neutrophils in company with intact neutrophils and, in lesions developed fully, with fibrin in the wall of venules. In septic vasculitis, neutrophils predominate, but are unaccompanied by nuclear…

Histologic Diagnosis of Inflammatory Skin Diseases

Behçet’s Disease

…blister that contained neutrophils and eosinophils, whereas signs of vasculitis, such a thrombi in the lumen of vessels and fibrin in the wall of them, were absent. Later in the process, sections were typified by changes prominent in blood vessels…

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