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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Persistent Lentiginous Melanocytic Hyperplasia, Atypical Melanocytic Hyperplasia (Melanocytic Nuclear Atypia), Lamellar Fibroplasia, Concentric Fibroplasia, and Lymphocytes as Criteria for Diagnosis Histopathologic of Dysplastic Nevi?

…ocytic hyperplasia (melanocytic nuclear atypia); (3) lamellar fibroplasias; (4) concentric eosinophilic fibroplasias; and (5) sparse, patchy lymphocytic infiltrates. This constellation of histologic findings, especially when present in two or more le…

A Clinical Atlas of 101 Common Skin Diseases

Dermatofibroma

An inflammatory process that develops secondary to trauma, usually in the form of a penetrating injury or rupture of a follicle, and that proceeds through stages of granulation tissue with numerous extravasated erythrocytes, granulomatous inflammati…

A Clinical Atlas of 101 Common Skin Diseases

Pyogenic Granuloma

…ntly from external trauma, usually in the form of a puncture or a yank of a “hang nail.” In time, the proliferation of vessels ceases, there is progressive fibroplasia, and the then gray or white papule shrinks and eventually disappears….

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Fibrosing Dermatitis

…5.355 A&B. Repair of chondrodermatitis nodularis helicis: fibroplasia characteristic of mending of an ulcer inflicted by trauma externally. The ulcer and granulation tissue of chondrodermatitis nodularis helicis are replaced by fibrosis of a scar…

Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…but they are not authentic scars. The same concept applies to fibroplasias that, in time, develop in the course of such dissimilar inflammatory diseases as lichen planopilaris (at the stage colloquially called pseudopelade of Brocq), traction alopeci…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…Figure 3.15 A. Fibrosis early. B. Fibrosis late (sclerosis). Fibroplasia is a synonym for fibrosis. When fibroplasia occurs in response to a benign or malignant neoplasm, it is called desmoplasia. Although the term fibrosis derives from the word &#8…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…hen, in some instances, papules of lichen planus resolve with fibroplasia superficial with loss consequent of dermal papillae and epidermal rete ridges, the result is hyperpigmented macules that sometimes are slightly delled (atrophic lichen planus)….

Histologic Diagnosis of Inflammatory Skin Diseases

Pyogenic granuloma

…but not completely, over the course of months; involuting by fibroplasia Variations clinical Lesions are widespread uncommonly. Differential diagnosis clinical Bacillary angiomatosis usually presents itself as many papules and nodules, sometimes hu…

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