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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Persistent Lentiginous Melanocytic Hyperplasia, Atypical Melanocytic Hyperplasia (Melanocytic Nuclear Atypia), Lamellar Fibroplasia, Concentric Fibroplasia, and Lymphocytes as Criteria for Diagnosis Histopathologic of Dysplastic Nevi?

…nocytic hyperplasia (melanocytic nuclear atypia); (3) lamellar fibroplasias; (4) concentric eosinophilic fibroplasias; and (5) sparse, patchy lymphocytic infiltrates. This constellation of histologic findings, especially when present in two or more l…

A Clinical Atlas of 101 Common Skin Diseases

Dermatofibroma

An inflammatory process that develops secondary to trauma, usually in the form of a penetrating injury or rupture of a follicle, and that proceeds through stages of granulation tissue with numerous extravasated erythrocytes, granulomatous inflammati…

A Clinical Atlas of 101 Common Skin Diseases

Pyogenic Granuloma

A red, often ulcerated, boggy papule that represents a hyperplasia of small cutaneous vessels which are "fed" by an arteriole in the subcutaneous fat, the lesion resulting consistently from external trauma, usually in the form of a punctur…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Fibrosing Dermatitis

See Fig. 5.350 A&B. Figure 5.350 Fibrosing dermatitis. A. Early. B. Late (sclerosis). Fibrosing dermatitis (as well as fibrosing peri-infundibulitis/perifolliculitis and fibrosing panniculitis) results, in every instance, from injury to nonep…

Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…by examination gross and by conventional microscopy. Moreover, fibroplasia does not necessarily denote fibrosing inflammation; it may be seen in a variety of benign and malignant neoplastic processes. For example, fibroplasia occurs in the papillary…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…Figure 3.15 A. Fibrosis early. B. Fibrosis late (sclerosis). Fibroplasia is a synonym for fibrosis. When fibroplasia occurs in response to a benign or malignant neoplasm, it is called desmoplasia. Although the term fibrosis derives from the word &#…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…d of the follicle is not thickened. In addition, pale-staining fibroplasia is seen to envelop infundibula in a manner that suggests strangulation of them. Later, fibroplasia is so extensive that infundibula and follicles, the entire length of them, b…

Histologic Diagnosis of Inflammatory Skin Diseases

Pyogenic granuloma

…ue histopathologically. Inevitably, that tissue is replaced by fibroplasia. If untreated, a pyogenic granuloma involutes with fibrosis. Some pyogenic granulomas resolve with the entire mass of tissue undergoing fibroplasia, the residual changes then…

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