Therapeutic Strategies in Dermatology

Flushing

Therapeutic Strategies in Dermatology

Flushing: Treatment

…underlying cause, if present, and then attempt to control the flushing. If an underlying cause cannot be determined, or if flushing persists after treatment of the primary problem, the therapeutic strategy is to control the flushing response by pharm…

Therapeutic Strategies in Dermatology

Flushing: Key Points

Key Points Flushing may be associated with a broad spectrum of underlying causes: medications, endocrine disease, neuroendocrine tumors, and neurologic diseases.  It is typically mediated by adrenergic hyperactivity, and only in rare cases is media…

Therapeutic Strategies in Dermatology

Rosacea: Key Points

…aris by the lack of comedones, identification of triggers for flushing, absence of scarring, the presence of phymatous changes, and the predilection to affect older adults rather than teenage adults. Rosacea patients often have sensitive skin and suf…

Therapeutic Strategies in Dermatology

Rosacea: Treatment

…and cosmetics. This subtype is best treated with avoidance of flushing, photoprotection, and surgical or laser therapies (see table, Subtype Directed Therapy). Though considered the mildest form of rosacea, the E-T subtype is marked by significant im…

Therapeutic Strategies in Dermatology

Rosacea: Clinical Cases

…ythemato-telangiectatic rosacea 55-year-old woman Chronic flushing, erythema and telangiectasias on cheeks, nose Not responding to topical antibiotics Treatment Discontinue topical antibiotics Topical brimonidine 0.33% gel (Mirvaso) Photoprotec…

Therapeutic Strategies in Dermatology

Flushing: Clinical Case

…1 32-year-old female presents with a history of intermittent flushing (face, neck, and upper chest), lasting 1 hour per episode, associated with abdominal pain and watery diarrhea. No associated triggers such as foods or other ingestions, also no si…

Therapeutic Strategies in Dermatology

Periorificial Dermatitis: Key Points

…acial cosmetics. In some cases, no triggering factors are found. Although it is considered by some to be related to rosacea, patients usually do not have flushing and other stigmata of rosacea. This condition affects young adult women most commonly….

Therapeutic Strategies in Dermatology

Rosacea: Initial Evaluation

…he face, sometimes with central facial edema. Associated with flushing. Phymatous subtype: Marked by thickening of the skin, irregular skin texture, edema, hypertrophy and hyperplasia of sebaceous glands, connective tissue, and v…

Therapeutic Strategies in Dermatology

Urticaria Pigmentosa / Mastocytosis: Treatment

…er. Ancillary steps H1 antihistamines can decrease itching, flushing, urticaria, and tachycardia. Both sedating and non-sedating antihistamines may offer some relief (diphenhydramine or hydroxyzine and cetirizine, respectively). Combination H1 and…