Search Results for: focal acantholytic dyskeratosis

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Therapeutic Strategies in Dermatology

Alopecia: Treatment

…sions with triamcinolone 2.5-10 mg/cc and if necessary repeat treatment every 4-6 weeks. Corticosteroid injections may cause focal reversible scalp depressions. Intralesional corticosteroid injections are not practical for patients with alopecia…

Therapeutic Strategies in Dermatology

Grover’s Disease / Transient Acantholytic Dermatosis: References

…uang V, Linette G, Cornelius L (2012). Unusual complication of vemurafenib treatment of metastatic melanoma: exacerbation of acantholytic dyskeratosis complicated by Kaposi varicelliform eruption, JAAD, 148:966-968. Norman R and Chau V (2011). Use…

Therapeutic Strategies in Dermatology

Grover’s Disease / Transient Acantholytic Dermatosis: Key Points

…medications have been reported in association with Grover’s disease. Introduction Grover’s disease, also known as transient acantholytic dermatosis (TAD), is a common pruritic condition that typically affects adult individuals and classically…

Dermoscopic clues to diagnose acantholytic dyskeratosis

Dermoscopic clues to diagnose acantholytic dyskeratosis

…, hair follicle changes, panniculitis, and photosensitivity [2], along with widespread eruptions with histologic features of acantholytic dyskeratosis [3]. Acantholytic dyskeratoma has been previously reported in association with other…

Therapeutic Strategies in Dermatology

Nummular Dermatitis: Overview

…in film twice daily. The eruption should disappear slowly over 3-6 weeks. Occlusion may enhance response and may be used for focal refractory lesions. Gentle skin care and daily hydration with moisturizers will enhance the treatment of nummular…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Clinical Case

…ure from crusted area Follow-up evaluation H&E demonstrates intraepidermal and suprabasal acantholysis without prominent dyskeratosis Bacterial culture was negative Initiate treatment with: aluminum chloride 20% solution, clindamycin 1%,…

Therapeutic Strategies in Dermatology

Darier’s Disease: References

…IJD, 44:184-192. Savignac M, Edir A, Simon M, Hovnanian A. (2011). Darier disease: a disease model of impaired calcium homeostasis in the skin, Biochimica et Biophysica Acta, 1813:1111-1117. Zeglaoui F, Zaraa I, Fazaa B, et al. (2005). Dyskeratosis

Therapeutic Strategies in Dermatology

Darier’s Disease: Key Points

…ticulum; the resulting disruption in calcium homeostasis in keratinocytes results in poor cell-cell adhesion with subsequent dyskeratosis affecting skin, nails, and mucous membranes. The hallmark skin lesion is a hyperkeratotic papule. The diagnosis…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Key Points

…s extending down to the suprabasal level, producing the characteristic “dilapidated brick wall” appearance in the epidermis. Dyskeratosis is not a prominent feature, in contrast to the findings seen in Darier’s disease. As HHD is not an…

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