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Therapeutic Strategies in Dermatology

Epidermolysis Bullosa: Overview

…ng: Since these diseases are inherited, genetic counseling is essential. Prenatal diagnosis via DNA testing is available for patients in whom previous pregnancies resulted in severely affected children. Family education: Some forms of EB are devastat…

Therapeutic Strategies in Dermatology

Psoriasis: Principles of Psoriasis Management

…scalp or palm/sole involvement Arthritis or nail involvement Generalized pustular and erythrodermic variants Topical therapy Phototherapy Systemic therapy Emollients Keratolytics Topical corticosteroids Vitamin D3 derivatives Tazarotene Tar…

Therapeutic Strategies in Dermatology

Photosensitivity Dermatoses: Overview

…ply. First Steps Maximum sun protection and sun avoidance is essential. These recommendations are for patients who have photosensitive skin diseases. Depending on the severity of the photosensitivity, more of the recommendations may need to be follo…

Therapeutic Strategies in Dermatology

Atopic Dermatitis: Principles of Management of Atopic Dermatitis

…be based on the extent (severity) of skin involvement (i.e., generalized vs. localized disease). Localized disease: usually managed by topical corticosteroids and liberal use of emollients, reduction of bacterial colonization, and reduction of prur…

Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease: Overview

…e an associated carcinoma. A careful lymph node evaluation is essential. Immunoperoxidase markers on paraffin fixed tissue can be used to identify the source of the primary carcinoma, or confirm that the lesion arose in the skin locally. Refer patien…

Therapeutic Strategies in Dermatology

Lichen Planus: Treatment

…duce antihistamines to levels necessary to control pruritus. Generalized lichen planus Initial therapy First-line treatment: Treat with oral prednisone (or an equivalent steroid) at 40-60 mg/day. Maintain the dose until symptoms abate and lesions cl…

Therapeutic Strategies in Dermatology

Granuloma Annulare: Key Points

…es. Granuloma annulare usually presents as localized disease, generalized plaques or papules, or subcutaneous nodules. Granuloma annulare may be associated with internal disease such as diabetes, hyperlipidemia, thyroid disease, or HIV, albeit in lim…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…aggressive disease (which may extend to underlying bone), and generalized disease. In areas endemic for HIV infection, AIDS-associated KS also occurs (see below). First Steps Localized cutaneous disease is managed like localized classic KS, with rad…

Therapeutic Strategies in Dermatology

Lichen Planus: Key Points

…s may be self-limited or chronic and presents as localized or generalized disease, usually with mild to severe pruritus. It affects 0.5-2% of the population, with women more commonly affected than men (3:1 female to male ratio in one study), presenti…

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