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Therapeutic Strategies in Dermatology

Epidermolysis Bullosa: Overview

…inherited in autosomal dominant fashion. . This disease may be generalized and severe (EB herpetiformis of Dowling-Meara), generalized and mild to moderate (Koebner type), or localized to the acral areas (Weber-Cockayne type). Scarring in general doe…

Therapeutic Strategies in Dermatology

Psoriasis: Principles of Psoriasis Management

Principles of Psoriasis Management Topical therapy is usually appropriate for treatment of patients with less than 10% body surface area (see table below). Systemic therapies (see table below) are indicated when one or more of the following are pre…

Therapeutic Strategies in Dermatology

Atopic Dermatitis: Principles of Management of Atopic Dermatitis

Principles of Management of Atopic Dermatitis Effective management must address 4 major issues: Skin barrier: Repairing the barrier through hydration and emollients Inflammation: Use of an anti-inflammatory agent, either topical or systemic In mos…

Therapeutic Strategies in Dermatology

Photosensitivity Dermatoses: Overview

Photosensitive drug eruptions, polymorphous light eruption, chronic actinic dermatitis (CAD -includes the conditions previously called photosensitive eczema, actinic reticuloid and persistent light reaction). Photosensitivity dermatoses are caused e…

Therapeutic Strategies in Dermatology

Granuloma Annulare: Overview

…treatments are usually reserved for patients with symptomatic generalized or ulcerating disease. Systemic retinoids, isotretinoin (40-80 mg daily) and acitretin (25-50 mg daily) may be attempted. Oral or bath PUVA may be effective for generalized l…

Therapeutic Strategies in Dermatology

Mucha-Habermann Disease: Overview

Pityriasis Lichenoides et Variolaformis Acuta / Pityriasis Lichenoides Chronica This condition is a benign and often self-limited lymphocytic vasculitis. Pityriasis lichenoides chronica (PLC) is treated like pityriasis lichenoides et varioliformis a…

Therapeutic Strategies in Dermatology

Allergic Contact Dermatitis: Treatment

Treatment First-line treatment: Limiting exposure to potential contactants is an essential first step. Topical measures to reduce inflammation are first-line treatment for limited disease, and systemic anti-inflammatory medications may be necessary…

Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease: Overview

Overview The diagnosis of Paget’s disease or extramammary Paget’s is made when Paget cells are identified in histopathologic specimens from involved skin. The term Paget’s disease is used when the cutaneous lesion is identified inv…

Therapeutic Strategies in Dermatology

Lichen Planus: Treatment

Treatment Localized lichen planus Initial therapy First-line treatment: Superpotent topical steroid ointment or cream. Apply superpotent fluorinated topical steroid ointment or cream such as fluocinonide (such as Lidex), betamethasone (such as Dipro…

Therapeutic Strategies in Dermatology

Atopic Dermatitis: Treatment

Treatment Initial therapy Hydration: Regular use of emollients during and between flares can provide effective hydration. See patient handout Skin Care in Atopic Dermatitis Suppression of inflammation: A topical corticosteroid should be applied…

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