Histologic Diagnosis of Inflammatory Skin Diseases

Gout

Gout Presentation stereotypical Age and sex Predominantly men Distribution of lesions Localized to ears and small joints, such as those of big toes Arrangement of lesions Discrete Individual lesions Papules, nodules, and even tumors Course Protracte…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Nodular and Diffuse Dermatitis

See Fig. 5.174 A&B. Figure 5.174 A&B. Nodular dermatitis and diffuse dermatitis. Nodular dermatitis is distinguished from perivascular dermatitis (see Fig. 5.16 A&B) by the density of the infiltrate of inflammatory cells. In the periv…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Hyalin?

“With the high power the hyaline is seen in very varied forms, which all show the same fuchsin red reaction. The first forms a section by itself; it comprises hyaline balls of different size, which lie free between the epithelial cells, and w…

Histologic Diagnosis of Inflammatory Skin Diseases

Silica granuloma

Silica granuloma Presentation stereotypical Age and sex No predilection Distribution of lesions On exposed sites usually Individual lesions Papules and nodules Course Protracted because the foreign body persists in the skin Findings histopathologic…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

“Blue nevus” (Jadassohn-Tièche) (Quiz #360) “Blue nevus” (Jadassohn-Tièche) (Quiz #525) “Blue nevus” (Masson’s blue neuronevus) (Quiz #359) “Collagenous” nevus, papillary dermal type* (Quiz #11…

Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiosis lipoidica

Necrobiosis lipoidica Synonyms Necrobiosis lipoidica diabeticorum Dermatitis atrophicans lipoidica diabetica Necrobiosis lipoidica granulomatosis Granulomatous tuberculoides pseudosclerodermiformis of Gottron Granulomatous disciformis chronica et pr…