Therapeutic Strategies in Dermatology

Herpes Simplex: Initial Evaluation

…of herpes are usually caused by herpes simplex type II. Herpetic whitlow may occur when digits are exposed to herpetic lesions. Eczema herpeticum, superinfection of atopic dermatitis with HSV, is common and can be difficult to distinguish f…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Treatment

Treatment Herpes zoster First-line therapy: The first-line therapy for herpes zoster includes the treatment of the acute eruption and therapy for herpetic neuralgia and post-herpetic neuralgia. Confirmation of herpes zoster by viral direct fluoresc…

Therapeutic Strategies in Dermatology

Erythema Multiforme: Clinical Cases

Clinical Cases Case 1 24-year-old woman with history of recurrent orolabial herpes infection Presents with asymptomatic lesions on the palms (approximately 8 on each hand) and soles (approximately 4-5 on each foot) that developed one day after n…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Key Points

Key Points Primary varicella infection (chickenpox) and herpes zoster are both caused by varicella zoster virus (VZV). Herpes zoster (shingles) represents activation of varicella zoster virus from cranial or dorsal root ganglion, thus affecting th…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: References

References Bruxelle J, Pinchinat S (2012) Effectiveness of antiviral treatment on acute phase of herpes zoster and development of post herpetic neuralgia: review of international publications, Med et Mal infectieuses (English), 42:53-58. Chen N, Li…

Therapeutic Strategies in Dermatology

Herpes Simplex: Key Points

Key Points Viral infections by herpes simplex (HSV) typically occur in two locations: the orofacial (usually type I) and genital (usually type II). Infections may be primary, recurrent, in the setting of immunosuppression, or superinfection of a pr…

Therapeutic Strategies in Dermatology

Herpes Simplex: Clinical Cases

Clinical Cases Case 1 7-year-old previously healthy girl with 2 days’ history of erythema on the right oral commissure and right lower cutaneous lip No fevers, chills, malaise No preceding illnesses or trauma Initial visit Obtain viral D…

Therapeutic Strategies in Dermatology

Folliculitis (including pseudofolliculitis barbae): Clinical Cases

Clinical Cases Case 1 18-year-old healthy male college student No significant past medical history Review of systems is noncontributory Presents for management of 7 days’ history of a pustular eruption on the face Initial evaluation Heal…

Therapeutic Strategies in Dermatology

Folliculitis (including pseudofolliculitis barbae): Treatment

Treatment Folliculitis First-line therapy: The first-line therapy for folliculitis includes the treatment of the appropriate cause, typically infection. A diagnostic biopsy or culture may be necessary to identify the inciting infectious cause. For…

Therapeutic Strategies in Dermatology

Darier’s Disease: Treatment

Treatment First-line therapy: The first-line therapy for Darier’s disease is systemic retinoids. First steps The currently accepted primary treatment of moderate-to-severe Darier’s disease is systemic retinoids. Isotretinoin and acitretin are equal…