A Clinical Atlas of 101 Common Skin Diseases

Nevus Sebaceus

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary lesio…

Differential Diagnosis in Dermatopathology

Discussions

Syringocystadenoma papilliferum and hidradenoma papilliferum are both apocrine papillated cystadenomas. Clinically, syringocystadenoma papilliferum appears at birth or in early childhood as a crusted, often weeping, verrucous plaque, usually on the…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eccrine Neoplasms?

…in various adnexal proliferations, such as syringocystadenoma papilliferum, hidradenoma papilliferum, and apocrine mixed tumor. Mature cells that compose normal sebaceous glands are characterized by abundant vacuolated cytoplasm that envelops a nucl…

Differential Diagnosis in Dermatopathology

Discussions

…t-like structures lined by a cuticle, the diagnosis is eccrine hidradenoma. That hidradenoma consists only of poroid cells (like those lateral to cells that line a normal acrosyringium) and cuticular cells (like those that line the lumen of an acrosy…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Basal-Cell Carcinoma Common in Nevus Sebaceus?

“Nevus sebaceus may be ‘programmed’ for or susceptible to the eventual development of a variety of neoplasms that generally occur in adulthood. The most common of these is basal cell carcinoma, which develops in 5% to 7% of the l…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Syringocystadenoma papilliferum Hidradenoma papilliferum 1. Not truly cystic (not a sac enclosed by epithelium) 1. Truly cystic (a sac enclosed completely or almost completely by epithelium) 2. Surface of skin papillated and hyperkeratotic 2….

Differential Diagnosis in Dermatopathology

Images

Syringocystadenoma papilliferum Hidradenoma papilliferum