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A Clinical Atlas of 101 Common Skin Diseases

Fixed Drug Eruption

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Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the genitalia, perioral region, and hands, in response to systemic administration of a particular drug or chemical, chief among them barbiturates and sulfonamides.

A Clinical Atlas of 101 Common Skin Diseases

Extramammary Paget’s Disease and Mammary Paget’s Disease

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Extramammary Paget’s disease is an apocrine carcinoma that begins within the epidermis and presents itself clinically as a patch or a subtle plaque that extends centrifugally for many years before becoming a readily discernible thick plaque, a finding that signifies involvement by the carcinoma of the dermis, too.

A Clinical Atlas of 101 Common Skin Diseases

Herpes Simplex, Zoster, and Varicella

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Conditions caused by infection with different strains of herpesvirus and typified when fully developed by tense vesicles, herpes simplex consisting of grouped vesicles on an erythematous base, zoster being made up of vesicles, sometimes hemorrhagic ones, that course along a dermatome of an adult usually, and varicella being characterized by widespread discrete vesicles in children as a rule.

A Clinical Atlas of 101 Common Skin Diseases

Histiocytosis X

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A proliferation of abnormal Langerhans’ cells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that may be localized (to the vulva, for example) or widespread.

A Clinical Atlas of 101 Common Skin Diseases

Phototoxic Dermatitis

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An inflammatory process that represents the combined effects of a toxic substance applied topically or administered systemically in combination with the effects of ultraviolet light, the result being a caricature of sunburn.

A Clinical Atlas of 101 Common Skin Diseases

Viral Exanthems

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An inflammatory process manifested by a transient, usually widespread eruption, made up typically of macules and papules, and episodically of vesicles and pustules.

A Clinical Atlas of 101 Common Skin Diseases

Xanthomas, Including Xanthogranulomas

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Deposits of lipid in the skin and sometimes in subcutaneous tissues as a consequence often, but not always, of hyperlipidemia.

A Clinical Atlas of 101 Common Skin Diseases

Xanthogranuloma

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A granulomatous inflammatory process that presents itself in children as multiple yellowish papules or nodules that often are associated with systemic involvement of eyes, liver, and testes.

A Clinical Atlas of 101 Common Skin Diseases

Histiocytosis X

A proliferation of abnormal Langerhans’ cells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that m…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses

A proliferation of abnormal Langerhans’ cells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that m…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…e and graft vs. host disease may closely mimic Langerhans cell histiocytosis. In Langerhans cell histiocytosis, most patients are immunologically normal prior to therapy when evaluated by standard tests. Morbidity and mortality may be reduced by appr…

Therapeutic Strategies in Dermatology

Candidiasis: Key Points

Key Points Candidiasis typically affects mucosal sites and moist and/or occluded areas of skin: groin, axilla, inframmary, infra-abdominal pannus, glans penis (in uncircumcised males), and orogenital mucosal sites. Predisposing factors include obe…

Therapeutic Strategies in Dermatology

Candidiasis: Treatment

Treatment First-line therapy: The first-line therapy should be specified for the affected anatomic site. Skin Initial therapy If the skin is macerated (e.g., moist, weeping), instruct the patient to soak in (or make an applied compress of) dilute…

Dermatology Practical & Conceptual

Langerhans cell histiocytosis-a case report

…pyright: ©2012 Jeunon et al.] Figure 3. (A) Langerhans cell histiocytosis, perineal lesion, scanning magnification. Note the dense band-like cellular infiltrate in the dermis and ulceration at the right side of the section (H&E, x20). (B) Band…

Histologic Diagnosis of Inflammatory Skin Diseases

Histiocytosis X

Histiocytosis X Presentation stereotypical Age and sex Children, boys mostly, and also adults Distribution of lesions Localized or widespread Individual lesions Red papules, purpuric papules, erosions, and ulcers Course Protracted, if not treated; s…

Differential Diagnosis in Dermatopathology

Mycosis fungoides, plaque vs. Histiocytosis X, plaque

A proliferation of abnormal Langerhans’ cells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that m…

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