Therapeutic Strategies in Dermatology

Syphilis (Lues): Key Points

…Cranial nerve dysfunction, meningitis, stroke, altered mental status, general paresis, tabes dorsalis Congenital syphilis Saddle nose Saber shin, Clutton’s joints, Higoumenakis sign, hepatosplenomegaly, neurosyphilis, pneumonitis, Hutchinson teeth

Therapeutic Strategies in Dermatology

Epidermolysis Bullosa: Overview

…nt may occur. Pyloric atresia is uniquely associated with JEB. Special Steps Children with JEB have hypoplastic dental enamel and resultant premature caries of both deciduous and permanent teeth. A skilled pediatric dentist must be a part of the hea…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…notype of a Langerhans cell that has been arrested at an early stage of activation and is functionally deficient. This disorder is classified as single-system disease, multisystem disease, or multisystem disease with organ dysfunction. The skin is on…

Therapeutic Strategies in Dermatology

Rosacea: Subtypes of Rosacea and Their Treatment

…o b.i.d. After initial clearance, the dosing may be reduced or stopped. Systemic tetracycline antibiotics should not be used in children under the age of 8 because of potential permanent discoloration of teeth. Macrolide antibiotics are an alternativ…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Treatment

…rapy: The first-line therapy for mild to moderate hidradenitis suppurativa is topical or systemic antibiotics. For very severe disease, systemic immunosuppression, specifically with anti-TNF-alpha inhibitors, may be first-line. First steps Medical C…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Key Points

…H) is an intensely pruritic, chronic disorder characterized by symmetrically distributed papulovesicles, bullae, or erosions. DH is an autoimmune blistering disease that is a cutaneous manifestation of gluten sensitivity. It is believed to be mediate…

A Clinical Atlas of 101 Common Skin Diseases

Polymorphous Light Eruption

An inflammatory process that appears on skin exposed to sunlight, especially the face, neck, sternal region, arms, and dorsa of hands, and consists mostly of edematous papules that may become confluent to form plaques, and at times, papulovesicles….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo Maligna?

…l. Progression to invasive melanoma from malignant melanoma in situ, lentigo maligna type. Hum Pathol 2000;31(6):705-8. It was Hutchinson, in his unique journal (every article during the 10 years of his tenure as editor of the Archives of Surgery, w…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pernio, Perniosis, Lupus Pernio, Chilblain, and Chilblain Lupus?

…d with cold exposure first was reported on in 1888 by Jonathan Hutchinson as he sought to classify the expressions clinical of lupus erythematosus (Harveian lectures on lupus, Brit Med J London 1:6–10). Hutchinson mentioned the tendency of hands, fin…